Comparative toxicity of eugenol and its quinone methide metabolite in cultured liver cells using kinetic fluorescence bioassays

DC Thompson, R Barhoumi, RC Burghardt - Toxicology and applied …, 1998 - Elsevier
Comparative kinetic analyses of the mechanisms of toxicity of the alkylphenol eugenol and
its putative toxic metabolite (quinone methide, EQM) were carried out in cultured rat liver …

Oxidative damage of mitochondrial and nuclear DNA induced by ionizing radiation in human hepatoblastoma cells

A Morales, M Miranda, A Sánchez-Reyes… - International Journal of …, 1998 - Elsevier
Purpose: Since reactive oxygen species (ROS) act as mediators of radiation-induced
cellular damage, the aim of our studies was to determine the effects of ionizing radiation on …

Mechanistic interactions of mycotoxins: theoretical considerations

RT Riley - Mycotoxins in Agriculture and Food Safety. Marcel …, 1998 - books.google.com
Mechanisms of mycotoxicity were recently reviewed by Riley and Norred [1]. This review
covered many of the mycotoxins that commonly occur on foods and feeds. In addition, it …

Analysis of Pb2+ Entry into Cultured Astroglia

ME Legare, R Barhoumi, E Hebert… - Toxicological …, 1998 - academic.oup.com
Astroglia serve as a presumptive lead (Pb) sink in the brain; therefore, this study examined
Pb entry into cultured rat astroglia utilizing the Ca2+ fluorophore indo-1 as a tool for …

My cotoxin Analytical Techniques

DM Wilson, EW Sydenham, GA Lombaert… - … in Agriculture and …, 1998 - taylorfrancis.com
Mycotoxin contamination of agricultural commodities is practically unavoidable due to
uncontrollable environmental conditions; however, the mycotoxin content of foods and feeds …

Synthesis of 13C-Labeled Patulin [4-Hydroxy-4H-furo[3,2-c]pyran-2(6H)-one] To Be Used as Internal Standard in a Stable Isotope Dilution Assay

M Rychlik, P Schieberle - Journal of agricultural and food …, 1998 - ACS Publications
A synthetic route was established for the preparation of [13C2]-4-hydroxy-4 H-furo [3, 2-c]
pyran-2 (6 H)-one (patulin) to be used in a stable isotope dilution assay. Mass spectral …

Attenuation of gossypol cytotoxicity by cyclic AMP in a rat liver cell line

RW Hutchinson, R Barhoumi, JM Miles… - Toxicology and applied …, 1998 - Elsevier
The effect of pretreatment of a rat liver cell line (Clone 9) with 8-bromo-cyclic adenosine
monophosphate (8-Br-cAMP), an agent previously shown to increase gap junctional …

[图书][B] The mechanism of gossypol acetic acid cytotoxicity

RW Hutchinson - 1998 - search.proquest.com
Gossypol is toxic to humans and animals, and has several potential therapeutic uses. The
biochemical mechanisms by which gossypol exerts cytotoxic effects were studied in the …