Vanecek, Jiri. Cellular Mechanisms of Melatonin Action. Physiol. Rev. 78: 687–721, 1998.—
The pineal hormone melatonin is involved in photic regulations of various kinds, including …

The present investigation used a placebo-controlled, double-blind, crossover design to
assess the sleep-promoting effect of three melatonin replacement delivery strategies in a …

Melatonin's timekeeping function is undoubtedly related to the fact that it is primarily
produced during nighttime darkness; that is, melatonin and light occur at opposite times. The …

To compare the impact of various dosage forms of melatonin and placebo on jet lag
symptoms, 320 volunteers who had flights over 6 to 8 time zones were recruited for a double …

Although light is the principal zeitgeber to the mammalian circadian system, other cues can
be shown to have a potent resetting effect on the clock of both adult and perinatal mammals …

The circadian secretion of melatonin by the pineal gland and retinae is a direct output of
circadian oscillators and of the circadian system in many species of vertebrates. This signal …

Although not licensed as a drug, melatonin is widely sold as a nutritional supplement in the
USA for its purported sleep-promoting and antiageing properties. In this article, we provide …

The pineal gland hormone melatonin is well known as a regulator of circadian rhythmicity,
but has also other functions in the central nervous system as well as in the periphery …

Study Design. A case-control study of 24-hour urinary melatonin production in patients with
adolescent idiopathic scoliosis. Objectives. To address the controversy over the role of …

Melatonin (MLT) is a methoxyindole secreted principally by the pineal gland. It is
synthesized at night under normal environmental conditions. The endogenous rhythm of …