Growth hormone and bone

C Ohlsson, BA Bengtsson, OGP Isaksson… - Endocrine …, 1998 - academic.oup.com
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Molecular regulation of insulin-like growth factor-I and its principal binding protein, IGFBP-3

LS Phillips, CI Pao, BC Villafuerte - Progress in nucleic acid research and …, 1998 - Elsevier
The insulin-like growth factors (IGFs) have diverse anabolic cellular functions, and structure
similar to that of proinsulin. The distribution of ICFs and their receptors in a wide variety of …

Treatment with the oral growth hormone secretagogue MK‐677 increases markers of bone formation and bone resorption in obese young males

J Svensson, C Ohlsson, JO Jansson… - Journal of Bone and …, 1998 - academic.oup.com
The effect of 2 months of treatment with the oral growth hormone (GH) secretagogue MK‐
677 on markers of bone metabolism was determined in healthy obese male subjects. This …

Calcium and insulin-like growth factor I stimulation of sodium-dependent phosphate transport and proliferation of cultured rat osteoblasts

C Schmid, C Keller, I Schläpfer, C Veldman… - … and biophysical research …, 1998 - Elsevier
Calcium (Ca) stimulates proliferation of osteoblasts in vitro, an effect proposed to be
mediated by IGF I. Addition of 1 mM Ca or of 1 nM IGF I to the medium (0.3 mM Ca) of a rat …

Insulin‐like growth factor binding proteins localize to discrete cell culture compartments in periosteal and osteoblast cultures from fetal rat bone

Y Chen, H Shu, C Ji, S Casinghino… - Journal of cellular …, 1998 - Wiley Online Library
Insulin‐like growth factor (IGF)‐I and IGF‐II are expressed at biologically effective levels by
bone cells. Their stability and activity are modulated by coexpression of IGF binding proteins …