Processing and properties of hydroxyapatite-based biomaterials for use as hard tissue replacement implants

W Suchanek, M Yoshimura - Journal of materials research, 1998 - cambridge.org
This paper reviews the past, present, and future of the hydroxyapatite (HAp)-based
biomaterials from the point of view of preparation of hard tissue replacement implants …

Development and scale‐up of a microsphere protein delivery system

MA Tracy - Biotechnology progress, 1998 - Wiley Online Library
This paper reviews the development path for the ProLease injectable microsphere delivery
system for proteins using human growth hormone as an example. The process consists of …

Use of molecular markers and major genes in the genetic improvement of livestock

HH Montaldo, CA Meza-Herrera - Electronic Journal of Biotechnology, 1998 - SciELO Chile
Recent developments in molecular biology and statistics have opened the possibility of
identifying and using genomic variation and major genes for the genetic improvement of …

The Effects of Porosity on in Vitro Degradation of Polylactic Acid–Polyglycolic Acid Implants Used in Repair of Articular Cartilage

KA Athanasiou, JP Schmitz, CM Agrawal - Tissue Engineering, 1998 - liebertpub.com
The objective of this study was to examine the effects of porosity on in vitro degradation
characteristics of an osteochondral biodegradable implant made of a 50: 50 copolymer of …

Poly (α‐hydroxyacids) for application in the spinal cord: Resorbability and biocompatibility with adult rat Schwann cells and spinal cord

SE Gautier, M Oudega, M Fragoso… - … Research: An Official …, 1998 - Wiley Online Library
Future surgical strategies to restore neurological function in the damaged human spinal cord
may involve replacement of nerve tissue with cultured Schwann cells using biodegradable …

Comparative histological evaluation of new tyrosine‐derived polymers and poly (L‐lactic acid) as a function of polymer degradation

KA Hooper, ND Macon, J Kohn - Journal of Biomedical …, 1998 - Wiley Online Library
Previous studies demonstrated that poly (DTE carbonate) and poly (DTE adipate), two
tyrosine‐derived polymers, have suitable properties for use in biomedical applications. This …

Early tissue reactions to polylactic acid resorbable membranes: a histological and histochemical study in rabbit

A Piattelli, A Scarano, F Coraggio, S Matarasso - Biomaterials, 1998 - Elsevier
The aim of this study, in rabbit tibia, was an evaluation of the early reactions of the tissues to
the insertion of polylactic membranes, used in connection with titanium implants. The …

Preparation and in vitro characterization of gentamycin-impregnated biodegradable beads suitable for treatment of osteomyelitis

JD Meyer, RF Falk, RM Kelly, JE Shively… - Journal of …, 1998 - Elsevier
Abstract□ A new method for preparing poly (L-lactide)(PLA) biodegradable beads
impregnated with an ionic aminoglycoside, gentamycin, is described. The process employs …

New technique to extend the useful life of a biodegradable cartilage implant

TL Spain, CM Agrawal, KA Athanasiou - Tissue Engineering, 1998 - liebertpub.com
Biodegradable implants made of α-hydroxypolyesters, such as polylactic acid, polyglycolic
acid, or their copolymers, undergo bulk degradation with a concomitant mass loss. Although …

Radiomorphometry and biomechanical assessment of recombinant human bone morphogenetic protein 2 and polymer in rabbit radius ostectomy model

DL Wheeler, DL Chamberland… - Journal of …, 1998 - Wiley Online Library
The study objective was to determine the mechanical integrity and radiopacity of
regenerated bone within critical‐sized defects (CSDs) in radii of rabbits using recombinant …