Treatment of rheumatoid arthritis with recombinant human interleukin‐1 receptor antagonist

B Bresnihan, JM Alvaro‐Gracia, M Cobby… - Arthritis & …, 1998 - Wiley Online Library
Objective To evaluate the efficacy and safety of interleukin‐1 receptor antagonist (IL‐1Ra) in
patients with rheumatoid arthritis (RA). Methods Patients with active and severe RA (disease …

Advances in the Treatment of Fibromyalgia: Current Status and FutureDirections

GS Alarcon, LA Bradley - The American journal of the medical sciences, 1998 - Elsevier
Despite significant efforts devotedto understanding the etiopathogenesis of fibromyalgia, its
treatment still presents achallenge to practicing clinicians, who must recognize the disorder …

Measuring health status in British patients with rheumatoid arthritis: reliability, validity and responsiveness of the short form 36-item health survey (SF-36).

DA Ruta, NP Hurst, P Kind, M Hunter… - British journal of …, 1998 - academic.oup.com
The objective was to assess the performance of the SF-36 health survey (SF-36) in a sample
of patients with rheumatoid arthritis (RA) stratified by functional class. The eight SF-36 …

Anti-tumor necrosis factor-α monoclonal antibody therapy for rheumatoid arthritis

AF Kavanaugh - Rheumatic Disease Clinics of North America, 1998 - Elsevier
Over the past few decades, the immunopathogenesis of rheumatoid arthritis (RA) has
become more clearly defined. 26, 35, 62 The initiation of this progressive, systemic …

Should imporvement in rheumatoid arthritis clinical trials be defined as fifty percent or seventy percent improvement in core set measures, rather than twenty percent?

DT Felson, JJ Anderson, MLM Lange… - … : Official Journal of …, 1998 - Wiley Online Library
Objective To determine whether improvement of more than 20% in core set parameters
should be required before patients are characterized as imporved in rheumatoid arthritis …

A standardized protocol for measurement of range of movement of the shoulder using the Plurimeter‐V inclinometer and assessment of its intrarater and interrater …

S Green, A Forbes, R Buchbinder… - Arthritis & Rheumatism …, 1998 - Wiley Online Library
Objective. To develop a standardized protocol for measurement of shoulder movements
using a gravity inclinometer designed for use in clinical trials, and to assess its intra‐and …

Cervical lesions related to the systemic progression in rheumatoid arthritis

K Fujiwara, M Fujimoto, H Owaki, J Kono, T Nakase… - Spine, 1998 - journals.lww.com
Study Design. Cross-sectional study of cervical involvement in rheumatoid arthritis.
Objectives. To clarify the correlation between the deterioration of cervical lesions and the …

Outcomes for persons with rheumatoid arthritis with a rheumatologist versus a non-rheumatologist as the main physician for this condition

EH Yelin, CL Such, LA Criswell, WV Epstein - Medical care, 1998 - journals.lww.com
Objective. The authors compared outcomes among persons with rheumatoid arthritis (RA)
with a rheumatologist versus a non-rheumatologist as the main physician for this condition …

Soluble tumor necrosis factor receptor (p75) fusion protein (ENBREL) as a therapy for rheumatoid arthritis

LW Moreland - Rheumatic Disease Clinics of North America, 1998 - Elsevier
Evidence supporting a role of tumor necrosis factor alpha (TNF-α) in the immune mediated
inflammatory process of rheumatoid arthritis (RA) has grown significantly over the past few …

Interleukin-1 receptor antagonist

B Bresnihan, G Cunnane - Rheumatic Disease Clinics, 1998 - rheumatic.theclinics.com
There are three members of the interleukin-1 (IL-1) gene family: IL-la, IL-lp, and IL-1 receptor
antagonist (IL-lra). 3, l9 IL-la and IL-1p are both agonist molecules which can influence the …