The Depression Guideline Panel of the Agency for Health Care Policy and Research in
1993 published recommendations for treating major depression in primary care practice that …

If the control rate (CR) in a clinical trial represents the incidence or the baseline severity of
illness in the study population, the size of treatment effects may tend to vary with the size of …

Summary Background Tricyclic antidepressants (TCAs) are associated with an increased
risk of falls and hip fractures in elderly people. Selective serotonin-reuptake inhibitors …

A meta‐analysis of the efficacy and tolerability of selective serotonin reuptake inhibitors
(SSRIs) against nonselective and noradrenergic reuptake inhibitors (mainly tricyclic …

Noncompliance remains one of the greatest challenges when prescribing psychotropic
medication and can render any treatment regimen wasteful and ineffective. While rates …

Background: This paper presents a nationwide analysis of suicide mortality in Finland from
1990 to 1995, when the total use of antidepressants, especially that by selective serotonin …

Depressive illness is a common, often unrecognised and untreated condition with
substantial associated costs, particularly indirect costs (eg lost productivity and …

Antidepressant drugs are among the most common drugs involved in fatal poisoning and
large variations between antidepressant drugs have been noted. Despite the fact that a …

Unipolar and bipolar depression are episodic, recurrent illnesses for the majority of patients.
Because each episode engenders considerable costs for patients, families, and society …

This article reviews the incidences of side effects in placebo-controlled clinical trials of drug
therapy in patients with panic disorder. We performed a MEDLINE search for placebo …