▪ Abstract We review concepts and methods for comparative analysis of complete genomes
including assessments of genomic compositional contrasts based on dinucleotide and …

Publisher Summary This chapter discusses the structure and function of DNA. DNA occupies
a critical role in cells, because it is the source of all intrinsic genetic information. Chemically …

The deformability of double helical DNA is critical for its packaging in the cell, recognition by
other molecules, and transient opening during biochemically important processes. Here, a …

The first nuclear magnetic resonance (NMR) spectrum of a protein was published some forty
years ago [l] and ever since, NMR of biological macromolecules has been a growing field in …

A sequence element located immediately upstream of the TATA element, and having the
consensus sequence 5′-G/CG/CG/ACGCC-3′, affects the ability of transcription factor IIB …

Neural network predictors of protein disorder using primary sequence information were
developed and applied to the Swiss Protein Database. More than 15,000 proteins were …

DNA bending in 86 complexes with sequence-specific proteins has been examined using
normal vector plots, matrices of normal vector angles between all base pairs in the helix, and …

The virulent phenotype of the pathogenic bacterium Corynebacterium diphtheriae is
conferred by diphtheria toxin, whose expression is an adaptive response to low …

The concept of CH… O hydrogen bonds has recently gained much interest, with a number of
reports indicating the significance of these non-classical hydrogen bonds in stabilizing …

Sso7d and Sac7d are two small (~ 7,000 M r), but abundant, chromosomal proteins from the
hyperthermophilic archaeabacteria Sulfolobus solfataricus and S. acidocaldarius …