Surfactant therapy is an established part of routine clinical management of babies with
respiratory distress syndrome. An initial dose of about 100 mg/kg is usually needed to …

▪ Abstract Genetic and phenotypic complexity has been described for diseases of varied
etiology. Groups of patients with varied phenotype can be used in association studies as an …

A 38-day-old male infant with persistent pulmonary hypertension and respiratory failure
since birth was found to have a complete absence of surfactant protein B (SP-B) along with …

Understanding surfactant composition, function, and therapeutic usefulness has increased
exponentially over the last 40 years. This article reviews the history and current …

The hydrophobic surfactant proteins, SP-B and SP-C, serve important roles in surfactant
function and metabolism. Both proteins are encoded by single genes, located on human …

We examined the ability of the human surfactant protein B (SP-B) promoter to confer cell
specificity of transgene expression in an adenoviral vector. Using similar replication …

We report on the DNA‐based prenatal diagnosis of congenital pulmonary alveolar
proteinosis in a family in which alveolar proteinosis was associated with surfactant protein B …

Publisher Summary This chapter outlines current knowledge on pulmonary surface and
surfactant investigations and targets at modelling of the surface-related interactions between …

Se realiza un estudio prospectivo, longitudinal en la Unidad de Cuidados Intensivos
Neonatal (UCIN) del Servicio de Pediatría, Hospital Dr. Luis E. Aybar, en Santo Domingo …

Patients with diffuse lung disease are among the most desperately ill in the Intensive Care
Unit (ICU). Clinicians caring for these patients must be adept at evaluating and treating …