▪ Abstract The formation of the vertebrate nervous system is initiated at gastrula stages of
development, when signals from a specialized cluster of cells (the organizer) trigger neural …

The origin and development of the amphibian somitie mesoderm is summarized and
reviewed with the goal of identifying issues most profitably pursued in these organisms. The …

The cellular and molecular mechanisms that regulate endoderm development in vertebrates
have only recently begun to be explored. Here we show that the zebrafish locus casanova …

The Eph receptor VAB-1 is required in neurons for epidermal morphogenesis during C.
elegans embryogenesis. Two models were proposed for the nonautonomous role of VAB-1 …

Signaling by members of the TGFβ superfamily is thought to be transduced by Smad
proteins. Here, we describe a zebrafish mutant in smad5, designated somitabun (sbn). The …

In many organisms, the primordial germ cells have to migrate from the position where they
are specified towards the developing gonad where they generate gametes. Extensive …

The dorsal gastrula organizer plays a fundamental role in establishment of the vertebrate
axis. We demonstrate that the zebrafish bozozok (boz) locus is required at the blastula …

A currently favored hypothesis postulates that a single field of cells in the neural plate forms
bilateral retinas. To learn how retinal precursors segregate, we followed individual labeled …

ABSTRACT A highly conserved TGF-β signaling pathway is involved in the establishment of
the dorsoventral axis of the vertebrate embryo. Specifically, Bone Morphogenetic Proteins …

Members of the bone morphogenetic protein (BMP) family actively promote ventral cell fates,
such as epidermis and blood, in the vertebrate gastrula. More dorsally, the organizer region …