Neural-tube defects

LD Botto, CA Moore, MJ Khoury… - New England journal of …, 1999 - Mass Medical Soc
Each year spina bifida and anencephaly, the two most common forms of neural-tube defects,
occur in 1 in 1000 pregnancies in the United States1 and an estimated 300,000 or more …

Prevention of neural-tube defects with folic acid in China

RJ Berry, Z Li, JD Erickson, S Li… - New England journal …, 1999 - Mass Medical Soc
Background Periconceptional use of multivitamins containing folic acid can reduce a
woman's risk of having a baby with a neural-tube defect. Methods As part of a public health …

[HTML][HTML] The effect of folic acid fortification on plasma folate and total homocysteine concentrations

PF Jacques, J Selhub, AG Bostom… - … England Journal of …, 1999 - Mass Medical Soc
Background In 1996, the Food and Drug Administration issued a regulation requiring all
enriched grain products to be fortified with folic acid to reduce the risk of neural-tube defects …

The role of folate transport and metabolism in neural tube defect risk

RC Barber, EJ Lammer, GM Shaw, KA Greer… - Molecular genetics and …, 1999 - Elsevier
Neural tube defects (NTDs) are common congenital malformations in humans. While
etiologically heterogeneous, for the most part they are multifactorial in their pathogenesis …

Maternal supplemental and dietary zinc intake and the occurrence of neural tube defects in California

EM Velie, G Block, GM Shaw… - American journal of …, 1999 - academic.oup.com
The authors investigated the association between maternal preconceptional supplemental
and dietary zinc intake and risk of neural tube defects (NTDs) in a population-based case …

Analysis of select folate pathway genes, PAX3, and human T in a midwestern neural tube defect population

D Trembath, AL Sherbondy, DC Vandyke… - …, 1999 - Wiley Online Library
Neural tube defects (NTDs) are a common birth defect, seen in approximately 1/1,000 births
in the United States. NTDs are considered a complex trait where several genes, interacting …

Periconceptional nutrient intake and risk for neural tube defect-affected pregnancies

GM Shaw, K Todoroff, DM Schaffer, S Selvin - Epidemiology, 1999 - journals.lww.com
We investigated whether intakes of nutrients, including of late, by women in the
periconceptional period were associated with risks of neural tube defect (NTD)-affected …

Achieving a public health recommendation for preventing neural tube defects with folic acid.

MM Werler, C Louik, AA Mitchell - American Journal of …, 1999 - ajph.aphapublications.org
OBJECTIVES: This study examined 3 approaches to achieving the public health
recommendation that all women of child-bearing age ingest 0.40 mg of folic acid per day to …

Folinic acid reduces cleft lip [CL (P)] in A/WySn mice

A Paros, SL Beck - Teratology, 1999 - Wiley Online Library
The A/WySnBk strain of mice displays 25–35% spontaneous CL (P). Pregnant mice were
treated with folinic acid continuously delivered via osmotic minipumps at the rate of 7.6±0.2 …

Prevalence of neural tube defects in the province of Quebec, 1992

P De Wals, C Trochet, L Pinsonneault - Canadian journal of public health, 1999 - Springer
A retrospective study of neural tube defects (NTDs) was carried out among elective
terminations of pregnancies, stillbirths and live births to women residing in two regions of …