Neural tissue is entirely dependent on glucose for normal metabolic activity. Since glucose
stores in the brain and retina are negligible compared to glucose demand, metabolism in …

Total GLUT4 content in skeletal muscle from individuals with type 2 diabetes is normal;
however, recent studies have demonstrated that translocation of GLUT4 to the plasma …

L6 myoblasts stably transfected with a GLUT4 cDNA harboring an exofacial myc epitope tag
(L6-GLUT4myc myoblasts) were used to study the role of protein kinase B alpha …

Insulin stimulates glucose uptake into muscle and fat cells by promoting the translocation of
glucose transporter 4 (GLUT4) to the cell surface. Phosphatidylinositide 3-kinase (PI3K) has …

The insulin‐sensitive glucose transporter (GLUT) 4, expressed primarily in peripheral tissue,
has recently been detected also in the brain, demonstrating a region‐specific distribution. To …

Chronic energy deficit is one of the strongest factors contributing to exercise-induced
menstrual dysfunction. In such cases, macro-and micronutrient intakes may also be low. This …

Prolonged exposure of 3T3-L1 adipocytes to insulin increases GLUT1 protein content while
diminishing GLUT4. These changes arise in part from changes in mRNA transcription. Here …

To identify potential proteins interacting with the insulin-responsive glucose transporter
(GLUT4), we generated fusion proteins of glutathione S-transferase (GST) and the final 30 …

GLUT4 is the major glucose transporter in adipose tissue and skeletal and cardiac muscles.
We examined the mechanisms underlying GLUT4 gene expression in 3T3-L1 cells, which …

Hypoxia is characterized by inadequate oxygen delivery to the myocardium with a resulting
imbalance between oxygen demand and energy supply. Several adaptive mechanisms …