The ALSFRS-R: a revised ALS functional rating scale that incorporates assessments of respiratory function

JM Cedarbaum, N Stambler, E Malta, C Fuller… - Journal of the …, 1999 - Elsevier
The ALS Functional Rating Scale (ALSFRS) is a validated rating instrument for monitoring
the progression of disability in patients with amyotrophic lateral sclerosis (ALS). One …

Experimental models of amyotrophic lateral sclerosis

JL Elliott - Neurobiology of disease, 1999 - Elsevier
Amyotrophic lateral sclerosis (ALS) is a chronic neurodegenerative disease characterized
by the progressive loss of motor neurons, leading to profound weakness and eventual death …

Motor unit number estimate–based rates of progression of ALS predict patient survival

C Armon, ME Brandstater - Muscle & Nerve: Official Journal of …, 1999 - Wiley Online Library
We have examined, as predictors of survival in patients with amyotrophic lateral sclerosis
(ALS), linear estimates of rates of disease progression (LEP), based on motor unit number …

Differential expression of brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4/5 in the adult rat spinal cord: regulation by the glutamate receptor …

IA Scarisbrick, PJ Isackson… - Journal of …, 1999 - Soc Neuroscience
Previous in vitro studies indicate that select members of the neurotrophin gene family,
namely brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and neurotrophin …

Practicing neurology: a delicate balance

SP Ringel - Neurology, 1999 - AAN Enterprises
As we near this end of the Decade of the Brain, we can all feel proud of the enormous
neuroscientific advances and improved treatments for our patients that we, collectively, have …