The objective of this article is to aid clinicians in understanding the current state of the
development and application of quality of life (QOL) instruments as outcome measures in …

The measurement of health-related quality of life (HRQL) in oncology clinical trials has come
of age. Most cooperative clinical trials groups as well as individual institutions have either …

The pharmaceutical industry, the medical device industry, and national regulatory agencies
such as the United States Food and Drug Administration (FDA) are faced with a number of …

PURPOSE: Alternatives to axillary lymph node dissection (ALND) are being developed amid
controversy surrounding the therapeutic benefit and overall utility of this routine surgical …

Purpose: To evaluate alternative automated methods of collecting data on quality of life
(QOL) in cancer patients. After initial evaluation of a range of technologies, we compared …

PURPOSE: To compare gemcitabine and cisplatin (GC) with mitomycin, ifosfamide, and
cisplatin (MIC) chemotherapy in patients with stage IIIB (limited to T4 for pleural effusion and …

The aim of this study was to describe prospectively quality of life and mood in patients with
oral or oropharyngeal cancer treated with surgery±radiotherapy. Seventy-five patients …

This study examined the usefulness of caregiver ratings of cancer patients' quality of life
(QOL), an issue of relevance to both adequate patient care and to the possible use of proxy …

Purpose: A combination of mitoxantrone plus prednisone is preferable to prednisone alone
for reduction of pain in men with metastatic, hormone-resistant, prostate cancer. The …

Background The aim of this study was to describe prospectively quality of life and mood
before and after radiotherapy for laryngeal cancer. Methods Sixty‐five patients with Tis‐T3 …