Lipopolysaccharide, the invariant structural component of Gram-negative bacteria, when
present in minute amounts in the circulation in humans elicitsendotoxic shock'syndrome …

Polymyxin B (PMB), a cyclic cationic peptide antibiotic, despite its severe side effects
continues to occupy a premiere position for treating endotoxicosis. Its mode of neutralization …

Micromolar concentrations of porin, purified from the outer membranes of Pseudomonas
aeruginosa, induced in vitro the classic morphological and biochemical signs of apoptosis in …

The protein SV‐IV, a major protein secreted from the rat seminal vesicle epithelium, is a
basic protein with immunomodulatory, anti‐inflammatory, and procoagulant activity …

抄録 E5531 is a specific lipid A antagonist and is expected to be a drug for the treatment of
septic shock. The LAL (limulus amebocyte lysate) activity and pyrogenicity of E5531 were …