Most adult humans are infected benignly and for life with the herpesvirus Epstein-Barr virus.
EBV has been a focus of research because of its status as a candidate tumor virus for a …

5 Function of Splenic Compartments............... 45 5. 1 Splenic White Pulp Compartments
during Primary T Cell-Dependent Antibody Responses against Protein …

Members of the tumor necrosis factor (TNF) family induce pleiotropic biological responses,
including cell growth, differentiation, and even death. Here we describe a novel member of …

Ag encounter will recruit Ag-specific cells from the pool of mature B lymphocytes in the
spleen and activate them to perform effector functions: generation of Ab-forming cells …

We have reported previously that in vitro generated dendritic cells (DC) can directly regulate
B cell responses. Recently, germinal center DC (GCDC) were identified within B cell …

To produce antibodies, the differentiation of B cells into antibody-secreting cells, plasma
cells, is required. We describe that ligation of CD27, which belongs to the tumor necrosis …

The activation antigen CD38, which has NAD+ glycohydrolase activity in its extracellular
domain, is expressed by a large variety of cell types. Few investigations into the regulation of …

Сокращения: Т—Т-клетки, Тх—Т-хелперы, Ти—Т-киллеры, В—В-лимфоциты, М—
моноциты/макрофаги, Г—гранулоциты, 3—эритроциты, МК—естественные киллеры …

Activated B cells and T cells express CD154/CD40 ligand in vitro. The in vivo expression
and function of B cell CD154 remain unclear and therefore were examined. Tonsillar B and …

Publisher Summary This chapter discusses the signaling pathways that are involved in
regulating B cell fate. The chapter begins with a brief overview of the rapidly advancing area …