Survival-and death-promoting events after transient cerebral ischemia: phosphorylation of Akt, release of cytochrome c, and activation of caspase-like proteases
YB Ouyang, Y Tan, M Comb, CL Liu… - Journal of Cerebral …, 1999 - journals.sagepub.com
Release of cytochrome c (cyt c) into cytoplasm initiates caspase-mediated apoptosis,
whereas activation of Akt kinase by phosphorylation at serine-473 prevents apoptosis in …
whereas activation of Akt kinase by phosphorylation at serine-473 prevents apoptosis in …
Estrogen and NGF synergistically protect terminally differentiated, ERα‐transfected PC12 cells from apoptosis
L Gollapudi, MM Oblinger - Journal of neuroscience research, 1999 - Wiley Online Library
The potential cytoprotective effects of the gonadal steroid estrogen, acting via its receptor
(ER) on target neurons, are of considerable interest in aging, disease, and trauma. In this …
(ER) on target neurons, are of considerable interest in aging, disease, and trauma. In this …
Motor neuron degeneration is attenuated in bax‐deficient neurons in vitro
O Bar‐Peled, M Knudson, SJ Korsmeyer… - Journal of …, 1999 - Wiley Online Library
Apoptosis plays a major role in motor neuron survival during developmental cell death, after
axotomy, and in motor neuron diseases. Bax is the first member of the bcl‐2 family shown to …
axotomy, and in motor neuron diseases. Bax is the first member of the bcl‐2 family shown to …
Neonatal ethanol exposure alters bcl‐2 family mRNA levels in the rat cerebellar vermis
DB Moore, DW Walker… - Alcoholism: Clinical and …, 1999 - Wiley Online Library
Background: The objective of the present work was to determine whether ethanol‐induced
cerebellar cell death during development is related to alterations in the expression of bcl‐2 …
cerebellar cell death during development is related to alterations in the expression of bcl‐2 …
Reciprocal changes in the expression of Bcl-2 and Bax in hypoglossal nucleus after axotomy in adult rats: possible involvement in the induction of neuronal cell death
N Baba, T Koji, M Itoh, A Mizuno - Brain research, 1999 - Elsevier
Numerous studies of neonatal neuronal development in mammals have revealed that
neuronal cell death following axotomy is apoptotic in nature. In adult animals, however …
neuronal cell death following axotomy is apoptotic in nature. In adult animals, however …
The role of early experience in olfactory bulb cell survival
B Johnson, M Leon - The biology of early influences, 1999 - Springer
Restriction of early sensory experience alters brain development, but the consequences of
reduced experience are particularly dramatic in the olfactory system. In other sensory …
reduced experience are particularly dramatic in the olfactory system. In other sensory …