Protein glucosylation and its role in protein folding
AJ Parodi - Annual review of biochemistry, 2000 - annualreviews.org
▪ Abstract An unconventional mechanism for retaining improperly folded glycoproteins and
facilitating acquisition of their native tertiary and quaternary structures operates in the …
facilitating acquisition of their native tertiary and quaternary structures operates in the …
Heat shock proteins–modulators of apoptosis in tumour cells
Apoptosis is a genetically programmed, physiological method of cell destruction. A variety of
genes are now recognised as positive or negative regulators of this process. Expression of …
genes are now recognised as positive or negative regulators of this process. Expression of …
A small heat shock protein cooperates with heat shock protein 70 systems to reactivate a heat-denatured protein
GJ Lee, E Vierling - Plant physiology, 2000 - academic.oup.com
Small heat shock proteins (sHsps) are a diverse group of heat-induced proteins that are
conserved in prokaryotes and eukaryotes and are especially abundant in plants. Recent in …
conserved in prokaryotes and eukaryotes and are especially abundant in plants. Recent in …
Polyglutamine length-dependent interaction of Hsp40 and Hsp70 family chaperones with truncated N-terminal huntingtin: their role in suppression of aggregation and …
NR Jana, M Tanaka, G Wang… - Human molecular …, 2000 - academic.oup.com
Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder caused by
polyglutamine expansion in the disease protein, huntingtin. In HD patients and transgenic …
polyglutamine expansion in the disease protein, huntingtin. In HD patients and transgenic …
Effects of heat shock, heat shock protein 40 (HDJ-2), and proteasome inhibition on protein aggregation in cellular models of Huntington's disease
A Wyttenbach, J Carmichael, J Swartz… - Proceedings of the …, 2000 - National Acad Sciences
Huntington's disease (HD), spinocerebellar ataxias types 1 and 3 (SCA1, SCA3), and
spinobulbar muscular atrophy (SBMA) are caused by CAG/polyglutamine expansion …
spinobulbar muscular atrophy (SBMA) are caused by CAG/polyglutamine expansion …
Protein renaturation by the liquid organic salt ethylammonium nitrate
CA Summers, RA Flowers - Protein Science, 2000 - cambridge.org
The room-temperature liquid salt, ethylammonium nitrate (EAN), has been used to enhance
the recovery of denatured-reduced hen egg white lysozyme (HEWL). Our results show that …
the recovery of denatured-reduced hen egg white lysozyme (HEWL). Our results show that …
Chaperones Hsp70 and Hsp40 suppress aggregate formation and apoptosis in cultured neuronal cells expressing truncated androgen receptor protein with …
Y Kobayashi, A Kume, M Li, M Doyu, M Hata… - Journal of Biological …, 2000 - ASBMB
Spinal and bulbar muscular atrophy (SBMA) is one of a group of human inherited
neurodegenerative diseases caused by polyglutamine expansion. We have previously …
neurodegenerative diseases caused by polyglutamine expansion. We have previously …
Roles of molecular chaperones in cytoplasmic protein folding
VR Agashe, FU Hartl - Seminars in cell & developmental biology, 2000 - Elsevier
Newly synthesized polypeptide chains must fold and assemble into unique three-
dimensional structures in order to become functionally active. In many cases productive …
dimensional structures in order to become functionally active. In many cases productive …
Molecular chaperone function of mammalian Hsp70 and Hsp40-a review
K Ohtsuka, M Hata - International Journal of Hyperthermia, 2000 - Taylor & Francis
Virtually all organisms respond to up-shifts in temperature (heat shock) by synthesizing a set
of proteins called heat shock proteins (HSPs). The HSPs are induced not only by heat shock …
of proteins called heat shock proteins (HSPs). The HSPs are induced not only by heat shock …
Roles of molecular chaperones in the nervous system
K Ohtsuka, T Suzuki - Brain research bulletin, 2000 - Elsevier
Heat shock proteins (HSPs) are induced not only by heat shock but also by various other
environmental stresses. HSPs such as Hsp90, Hsp70, Hsp60, Hsp40 and Hsp28 are also …
environmental stresses. HSPs such as Hsp90, Hsp70, Hsp60, Hsp40 and Hsp28 are also …