Membrane breakdown in acute and chronic neurodegeneration: focus on choline-containing phospholipids

J Klein - Journal of neural transmission, 2000 - Springer
Breakdown of cellular membranes is a characteristic feature of neuronal degeneration in
acute (stroke) and chronic (senile dementia) neurological disorders. The present review …

Alcohol: its metabolism and interaction with nutrients

CS Lieber - Annual review of nutrition, 2000 - annualreviews.org
In the past, alcoholic liver disease was attributed exclusively to dietary deficiencies, but
experimental and judicious clinical studies have now established alcohol's hepatotoxicity …

Choline: an essential nutrient for humans

SH Zeisel - Nutrition, 2000 - Elsevier
Choline is needed for synthesis of the phospholipids in cell membranes, methyl metabolism,
cholinergic neurotransmission, transmembrane signaling, and lipid-cholesterol transport …

Choline: needed for normal development of memory

SH Zeisel - Journal of the American College of Nutrition, 2000 - Taylor & Francis
Choline is a dietary component essential for normal function of all cells. It, or its metabolites,
assures the structural integrity and signaling functions of cell membranes; it is the major …

Metabolic and nutritional considerations in nonalcoholic fatty liver

DG Fong, V Nehra, KD Lindor, AL Buchman - Hepatology, 2000 - journals.lww.com
Fatty liver, or steatosis, refers to a histopathologic condition characterized by the excess
accumulation of lipids within hepatocytes. Although various classes of lipids may …

Neonatal choline supplementation ameliorates the effects of prenatal alcohol exposure on a discrimination learning task in rats

JD Thomas, MH La Fiette, VRE Quinn… - Neurotoxicology and …, 2000 - Elsevier
Prenatal alcohol exposure can disrupt brain development and lead to a myriad of behavioral
alterations, including motor coordination deficits, hyperactivity, and learning deficits. There …

[PDF][PDF] Protective effects of prenatal choline supplementation on seizure-induced memory impairment

Y Yang, Z Liu, JM Cermak, P Tandon… - The Journal of …, 2000 - Soc Neuroscience
Choline is an essential nutrient for rats and humans, and its availability during fetal
development has long-lasting cognitive effects (Blusztajn, 1998). We investigated the effects …

Hepatic, metabolic, and nutritional disorders of alcoholism: from pathogenesis to therapy

CS Lieber - Critical reviews in clinical laboratory sciences, 2000 - Taylor & Francis
Much progress has been made in the understanding of the pathogenesis of alcoholic liver
disease, resulting in an improvement in treatment. Nutritional deficiencies should be …

[HTML][HTML] Choline is required by tilapia when methionine is not in excess

CS Kasper, MR White, PB Brown - The Journal of nutrition, 2000 - Elsevier
Choline is essential in diets fed to most young vertebrates, but previous studies did not
confirm the essentiality of choline in diets fed to tilapia. Two experiments were conducted to …

[HTML][HTML] Caffeine, carnitine and choline supplementation of rats decreases body fat and serum leptin concentration as does exercise

N Hongu, DS Sachan - The Journal of nutrition, 2000 - Elsevier
The effect of a combination of caffeine, carnitine and choline with or without exercise on
changes in body weight, fat pad mass, serum leptin concentration and metabolic indices …