X-linked immunodeficiency with hyper-IgM (XHIM)
LD Notarangelo, AR Hayward - Clinical & Experimental …, 2000 - academic.oup.com
Immunodeficiency with hyper-IgM was described by Israel-Asselain et al. in 1960 [1] and
Rosen et al. in 1962 [2]. It is characterized by recurrent infections, very low or undetectable …
Rosen et al. in 1962 [2]. It is characterized by recurrent infections, very low or undetectable …
[HTML][HTML] Cytokines and T cells in host defense
CA Hunter, SL Reiner - Current opinion in immunology, 2000 - Elsevier
Soluble and cell-bound ligands profoundly influence the differentiative fate of lymphocytes
during an immune response. Recent advances have been made in understanding the role …
during an immune response. Recent advances have been made in understanding the role …
Measles virus induces abnormal differentiation of CD40 ligand-activated human dendritic cells
C Servet-Delprat, PO Vidalain, H Bausinger… - The Journal of …, 2000 - journals.aai.org
Measles virus (MV) infection induces a profound immunosuppression responsible for a high
rate of mortality in malnourished children. MV can encounter human dendritic cells (DCs) in …
rate of mortality in malnourished children. MV can encounter human dendritic cells (DCs) in …
Transcriptional activity of the distal CD40 ligand promoter
FM Lobo, S Xu, C Lee, RL Fuleihan - Biochemical and Biophysical …, 2000 - Elsevier
CD40 ligand (CD40L, CD154) is a T cell cytokine with highly regulated expression that
requires the transcription factor nuclear factor of activated T cells (NF-AT) to bind at two sites …
requires the transcription factor nuclear factor of activated T cells (NF-AT) to bind at two sites …
Absence of CD40–CD40 ligand interactions in X-linked hyper-IgM syndrome does not affect differentiation of T helper cell subsets
H Uronen, RE Callard - Clinical & Experimental Immunology, 2000 - academic.oup.com
The aim of this study was to investigate the effect of absent CD40–CD40 ligand interactions
in patients with X-linked hyper–IgM syndrome (XHIGM) on the generation of Th1 and Th2 …
in patients with X-linked hyper–IgM syndrome (XHIGM) on the generation of Th1 and Th2 …