Identification of potent, selective non-peptide CC chemokine receptor-3 antagonist that inhibits eotaxin-, eotaxin-2-, and monocyte chemotactic protein-4-induced …

JR White, JM Lee, K Dede, CS Imburgia… - Journal of Biological …, 2000 - ASBMB
Eosinophils have been implicated in the pathogenesis of asthma and other allergic
diseases. Several CC chemokines including eotaxin (CCL-11), eotaxin-2 (CCL-24) …

[PDF][PDF] Identification of potent, selective non-peptide CCR3 antagonist that inhibits eotaxin-, eotaxin-2 and MCP-4 induced eosinophil migration

JR White, JM Lee, K Dede, CS Imburgia… - J Biol …, 2000 - researchgate.net
Several CC chemokines including eotaxin (CCL-11), eotaxin-2 (CCL-24), RANTES (CCL-5),
monocyte chemotactic protein-3 (MCP-3, CCL-7) and 4 (MCP-4, CCL-13) are potent …

Antagonist of chemokine receptors CCR1 and CCR3

A Ammit - Respiratory Research, 2000 - Springer
Trafficking and activation of leukocytes plays a significant role in the initiation and
perpetuation of airway inflammation and bronchial hyperreactivity in asthma. The chemokine …