RNA-DNA interactions can serve as a signal that triggers de novo DNA methylation in
plants. As yet, this RNA-directed DNA methylation mechanism merely targets transgenes …

Genomic imprinting, a process that causes genes to be expressed according to their
parental origin, affects a minority of human genes, probably less than 1,000. Nevertheless …

The KvLQT1 gene encodes a voltage-gated potassium channel. Mutations in KvLQT1
underlie the dominantly transmitted Ward-Romano long QT syndrome, which causes cardiac …

In marsupials and in extraembryonic tissues of placental mammals, X inactivation is
imprinted to occur on the paternal chromosome. Here, we find that imprinting is controlled by …

Unusually large offspring have been born in ruminants following the transfer to recipients of
embryos that have either been subjected to some form of manipulation, eg nuclear transfer …

Beckwith-Wiedemann syndrome (BWS) is a model imprinting disorder resulting from
mutations or epigenetic events involving imprinted genes at chromosome 11p15. 5. Thus …

Abstract Human chromosome 11p15. 5 harbors an intriguing imprinted gene cluster of 1 Mb.
This imprinted domain is implicated in a wide variety of malignancies and Beckwith …

The Gnas locus in distal mouse chromosome (Chr) 2 is emerging as a complex genomic
region. It contains three imprinted genes in the order Nesp-Gnasxl-Gnas. Gnas encodes a G …

Recent studies of the GNAS1 gene have shown a highly complex imprinted expression
pattern, with paternally, maternally and biallelically derived pro‐tein products, raising …

Imprinted genes represent a curious defiance of normal Mendelian genetics. Mammals
inherit two complete sets of chromosomes, one from the mother and one from the father, and …