Sambucus nigra (elder) has been documented as a traditional treatment of diabetes. In the
present study, an aqueous extract of elder (AEE, 1 g/L) significantly increased 2-deoxy …

Functional effects of prolonged exposure to the sulphonylurea glibenclamide were
examined in a popular clonal pancreatic β-cell line, denoted as BRIN-BD11. In acute 20-min …

Effect of type-selective inhibitors on cyclic nucleotide phosphodiesterase activity and insulin
secretion in the clonal insulin secreting cell line BRIN-BD11 - PMC Back to Top Skip to main …

Ovarian development, follicular growth and atresia require mechanisms regulating
proliferation and death of ovarian cells including theca-interstitial (TI) cells. Transforming …

The aim of our study was to develop a method for selection of subpopulations of insulin
producing RINm cells with higher resistance to beta cell toxins. Cells, resistant to …

We report here that the cyclic GMP-inhibited cyclic AMP specific phosphodiesterase
(PDE3B) is expressed as a membrane-bound protein in clonal insulin-secreting BRIN-BD11 …

Acute and chronic mechanisms of action of novel insulinotropic antidiabetic drug, BTS 67
582 (1, 1‐dimethyl‐2‐(2‐morpholinophenyl) guanidine fumarate), were examined in the …

KATP-channel-dependent and KATP-channel-independent insulin-releasing actions of the
sulfonylurea, tolbutamide, were examined in the clonal BRIN-BD11 cell line. Tolbutamide …

There are conflicting reports on the effect of serum from patients with insulin-dependent
diabetes mellitus (IDDM) or normal human serum on β-cell function and insulin secretion …

In view of the advantages of the bulk production of clonal pancreaticbeta cells, an
investigation was made of the growth and insulin secretoryfunctions of an electrofusion …