The neurobiology of stress and gastrointestinal disease

EA Mayer - Gut, 2000 - gut.bmj.com
Systemic or interoceptive stressors, 28 in the context of the four chronic gastrointestinal
disorders listed above, can occur in the form of mucosal inflammation (IBD, PUD) or tissue …

Biological mechanisms of acupuncture

DJ Mayer - Progress in brain research, 2000 - Elsevier
This chapter will begin by briefly placing modem acupuncture in an historical context. This
will lead, in the following section, to a discussion of some technical difficulties and limitations …

Descending facilitatory modulation of a behavioral nociceptive response by stimulation in the adult rat anterior cingulate cortex

AA Calejesan, SJ Kim, M Zhuo - European Journal of Pain, 2000 - Elsevier
It is well documented that the descending endogenous analgesia system, including the
periaqueductal gray (PAG) and the rostral ventral medulla (RVM), play an important role in …

Age-related differences in the endogenous analgesic response to repeated cold water immersion in human volunteers

LL Washington, SJ Gibson, RD Helme - Pain, 2000 - journals.lww.com
Recent animal studies using stress-induced analgesia have suggested a general age-
related decline in endogenous pain inhibitory systems. The aim of the current study was to …

Antinociception induced by amitriptyline and imipramine is mediated by α2A-adrenoceptors

C Ghelardini, N Galeotti, A Bartolini - The Japanese Journal of …, 2000 - jstage.jst.go.jp
The involvement of az-adrenoceptors in the antinociception induced by the tricyclic
antidepressants amitriptyline and imipramine was investigated in mice by using the hot-plate …

Presynaptic and postsynaptic relations of μ‐opioid receptors to γ‐aminobutyric acid‐immunoreactive and medullary‐projecting periaqueductal gray neurons

KG Commons, SA Aicher, LM Kow… - Journal of Comparative …, 2000 - Wiley Online Library
The ventrolateral portion of the periaqueductal gray (PAG) is one brain region in which
ligands of the μ‐opioid receptor (MOR) produce analgesia. In the PAG, MOR ligands are …

Pressure pain thresholds and electromyographically defined muscular fatigue induced by a muscular endurance test in normal women

AL Persson, GÅ Hansson, J Kalliomäki… - The Clinical journal …, 2000 - journals.lww.com
Objective: This study was undertaken to examine the relation between muscular tenderness
measured as pressure pain thresholds (PPTs) and electromyographic (EMG) signs of fatigue …

Efficacy of sustained-release bupropion in neuropathic pain: an open-label study

MR Semenchuk, B Davis - The Clinical journal of pain, 2000 - journals.lww.com
Objective: The purpose of this study was to assess the analgesic potential of sustained-
release (SR) bupropion for neuropathic pain. Design: Open-label treatment design. Setting …

DL-phenylalanine markedly potentiates opiate analgesia–an example of nutrient/pharmaceutical up-regulation of the endogenous analgesia system

AL Russell, MF McCarty - Medical hypotheses, 2000 - Elsevier
In the author's clinical experience, concurrent treatment with DL-phenylalanine (DLPA) often
appears to potentiate pain relief and also ease depression in patients receiving opiates for …

Integration of viscerosomatic sensory input at the spinal level

RD Foreman - Progress in brain research, 2000 - Elsevier
Throughout the history of medicine, headache pain has afflicted human beings. People have
sought relief from the physician, medicine man, shaman and others who use complementary …