We review here our work on the molecular and functional organization of endothelial cell-to-
cell junctions. The first part of the review is dedicated to VE-cadherin, characterized by our …

Endothelial cell contacts control the permeability of the blood vessel wall. This allows the
endothelium to form a barrier for solutes, macromolecules, and leukocytes between the …

Ets1 is a transcription factor expressed in endothelial cells during angiogenesis but its target
genes and function in blood vessel formation are still unknown. We have over-expressed …

Endothelium-derived nitric oxide (NO) is primarily attributable to constitutive expression of
the endothelial nitric oxide synthase (eNOS) gene. Although a more comprehensive …

Vascular endothelial growth factor (VEGF) signaling is required for both differentiation and
proliferation of vascular endothelium. Analysis of differentiated embryonic stem cells with …

PROBLEM: Angiogenesis and vasculogenesis appear to be of critical importance for the
success of pregnancy. Recent data have emphasized that pregnancy complications, such as …