Cannabinoid research underwent a tremendous increase during the last 10 years. This
progress was made possible by the discovery of cannabinoid receptors and the …

The purpose of this review is to discuss the cellular synthesis and inactivation of two putative
endogenous ligands of the cannabinoid receptor, N-arachidonylethanolamine (AEA) and 2 …

The effect of cannabinoids on the induction of cytokine mRNA by rat microglial cells was
examined. Exposure of neonatal rat cortical microglial cells to the exogenous cannabinoid …

The midbrain periaqueductal gray (PAG) is a major site of cannabinoid-mediated analgesia
in the central nervous system. In the present study, we examined the actions of …

Anandamide (arachidonylethanolamide) and 2-arachidonoylglycerol mediate many of their
actions via either CB1 or CB2 cannabinoid receptor subtypes. These agonist-receptor …

This review highlights some important advances that have taken place in cannabinoid
research over the last four years. It focuses on novel ligands that are of interest either as …

Many of the pharmacological effects of Δ9-tetrahydrocannabinol are mediated through CB1
and CB2 cannabinoid receptors. However, with the discovery of endogenous cannabinoids …

Previous studies have shown that mice primed with Corynebacterium parvum produce
higher levels of inflammatory cytokines than unprimed mice upon challenge with …

We used spontaneously active neuronal networks derived from dissociated embryonic
murine spinal cord and auditory cortex and grown on substrate-integrated thin-film …

Anandamide (N-arachidonylethanolamide) is an endogenous cannabinoid that mimics the
pharmacologic effects of Δ9-tetrahydrocannabinol, the major bioactive substance in …