Iron metabolism in pathogenic bacteria

C Ratledge, LG Dover - Annual reviews in microbiology, 2000 - annualreviews.org
▪ Abstract The ability of pathogens to obtain iron from transferrins, ferritin, hemoglobin, and
other iron-containing proteins of their host is central to whether they live or die. To combat …

Iron and oxidative stress in bacteria

D Touati - Archives of biochemistry and biophysics, 2000 - Elsevier
The appearance of oxygen on earth led to two major problems: the production of potentially
deleterious reactive oxygen species and a drastic decrease in iron availability. In addition …

Identification of the Escherichia coli K‐12 Nramp orthologue (MntH) as a selective divalent metal ion transporter

H Makui, E Roig, ST Cole, JD Helmann… - Molecular …, 2000 - Wiley Online Library
The Escherichia coli mntH (formerly yfeP) gene encodes a putative membrane protein
(MntH) highly similar to members of the eukaryotic Nramp family of divalent metal ion …

The mammalian neuroendocrine hormone norepinephrine supplies iron for bacterial growth in the presence of transferrin or lactoferrin

PPE Freestone, M Lyte, CP Neal, AF Maggs… - Journal of …, 2000 - Am Soc Microbiol
Norepinephrine stimulates the growth of a range of bacterial species in nutritionally poor
SAPI minimal salts medium containing 30% serum. Addition of size-fractionated serum …

The structure of the ferric siderophore binding protein FhuD complexed with gallichrome

TE Clarke, SY Ku, DR Dougan, HJ Vogel… - Nature structural …, 2000 - nature.com
Siderophore binding proteins play a key role in the uptake of iron in many gram-positive and
gram-negative bacteria. FhuD is a soluble periplasmic binding protein that transports …

Heterogeneity of iron bioavailability on plants assessed with a whole-cell GFP-based bacterial biosensor

DC Joyner, SE Lindow - Microbiology, 2000 - microbiologyresearch.org
Ferric iron is an essential element for microbial growth but its water solubility in aerobic
environments is considered to be low. Thus it is a limiting resource for which microbes must …

Molecular characterization of the ferric-uptake regulator, Fur, from Staphylococcus aureus

A Xiong, VK Singh, G Cabrera… - Microbiology, 2000 - microbiologyresearch.org
Iron is an essential nutrient for the survival and pathogenesis of bacteria, but relatively little
is known regarding its transport and regulation in staphylococci. Based on the known …

Iron chelators from mycobacteria (1954–1999) and potential therapeutic applications

AF Vergne, AJ Walz, MJ Miller - Natural Product Reports, 2000 - pubs.rsc.org
041disk doc..041disk chapter .. Page99 Page 1 Iron chelators from mycobacteria (1954–1999)
and potential therapeutic applications Anne F. Vergne, Andrew J. Walz and Marvin J. Miller …

Discovery of a Nonclassical Siderophore, Legiobactin, Produced by Strains of Legionella pneumophila

MR Liles, TA Scheel, NP Cianciotto - Journal of bacteriology, 2000 - Am Soc Microbiol
The mechanisms by which Legionella pneumophila, a facultative intracellular parasite and
the agent of Legionnaires' disease, acquires iron are largely unexplained. Several earlier …

Nitrate regulation of Fe reduction and transport by Fe‐limited Thalassiosira oceanica

MT Maldonado, NM Price - Limnology and Oceanography, 2000 - Wiley Online Library
Under Fe‐limiting conditions, nitrate (NO3−)‐grown marine diatoms have higher intracellular
Fe requirements, but divide as fast or faster than ammonium (NH4+)‐grown cells by …