Germline mutations of the APC gene in patients with familial adenomatous polyposis-associated thyroid carcinoma: results from a European cooperative study

F Cetta, G Montalto, M Gori, MC Curia… - The Journal of …, 2000 - academic.oup.com
Papillary thyroid carcinoma (PTC) is one extracolonic manifestation affecting about 1–2% of
patients with familial adenomatous polyposis (FAP). Ninety-seven patients with FAP …

Role of ras mutation in the progression of thyroid carcinoma of follicular epithelial origin

N Motoi, A Sakamoto, T Yamochi, H Horiuchi… - … -Research and Practice, 2000 - Elsevier
The histological differentiation of thyroid carcinoma is known to correlate with prognosis.
Ras oncogene mutations, which have been identified in various human cancers, have been …

Molecular pathogenesis of thyroid nodules and cancer

F Moretti, S Nanni, A Pontecorvi - Best Practice & Research Clinical …, 2000 - Elsevier
Tumours derived from the thyroid follicular epithelium represent an informative model for
understanding the molecular pathogenesis of multistage tumourigenesis, which is the …

The changing incidence and spectrum of thyroid carcinoma in Tasmania (1978–1998) during a transition from iodine sufficiency to iodine deficiency

JR Burgess, T Dwyer, K McArdle… - The Journal of …, 2000 - academic.oup.com
Exposure to ionizing radiation, changing levels of iodine nutrition, and increased pathologic
diagnosis of clinically unimportant thyroid neoplasia have all been proposed as …

Molecular genetics of thyroid tumors and surgical decision-making

DL Learoyd, M Messina, J Zedenius… - World journal of surgery, 2000 - Springer
The study of thyroid tumor genetics has great relevance to surgeons and facilitates
understanding tumor pathogenesis, prediction of tumor behavior, and management …

Multiple ras downstream pathways mediate functional repression of the homeobox gene product TTF-1

C Missero, MT Pirro, R Di Lauro - Molecular and cellular biology, 2000 - Taylor & Francis
Expression of oncogenic Ras in thyroid cells results in loss of expression of several thyroid-
specific genes and inactivation of TTF-1, a homeodomain-containing transcription factor …

TRAIL-induced apoptosis of thyroid cancer cells: potential for therapeutic intervention

M Ahmad, Y Shi - Oncogene, 2000 - nature.com
To determine whether the apoptotic machinery of thyroid cancer cells is functional and could
be activated for tumoricidal purposes, we examined the apoptosis induced by the cytokines …

Effects of exogenous p53 transduction in thyroid tumor cells with different p53 status

F Moretti, S Nanni, A Farsetti, M Narducci… - The Journal of …, 2000 - academic.oup.com
Recovery of p53 function in undifferentiated thyroid carcinoma cells carrying an altered p53
gene is able to modify cell tumorigenic properties. It is not known whether such an effect may …

Молекулярно-генетические аспекты новообразований щитовидной железы

ИИ Дедов, ЕА Трошина… - Проблемы …, 2000 - probl-endojournals.ru
Аннотация Профилактика, диагностика и лечение новообразований щитовидной
железы представляют собой одну из самых актуальных проблем современной …

Expression patterns of cellular growth-controlling genes in non-medullary thyroid cancer: basic aspects

NJ Sarlis - Reviews in Endocrine and Metabolic Disorders, 2000 - Springer
Expression Patterns of Cellular Growth-Controlling Genes in Non-Medullary Thyroid Cancer:
Basic Aspects | Reviews in Endocrine and Metabolic Disorders Skip to main content SpringerLink …