The intensity of expression of the chemokine receptor CCR5 is involved in in vitro cell
infectability by human immunodeficiency virus (HIV)-1 R5 isolates. Because CCR5 …

▪ Abstract In an age when the majority of monogenic human disease genes have been
identified, a particular challenge for the coming generation of human geneticists will be …

To test the hypothesis that β-chemokine levels may be relevant to the control of HIV in vivo,
we compared RANTES, MIP-1α, and MIP-1β production from purified CD8+ T cells from 81 …

Chemokines and matrix metalloproteinases (MMPs) appear to be crucial in leukocyte
recruitment to the central nervous system in multiple sclerosis (MS). CCR5 Δ32, a truncated …

The human immunodeficiency virus type 1 (HIV-1) infection is characterized by a long and
often prolonged asymptomatic period after initial infection. A number of early …

The effects of chemokine and chemokine receptor genetic polymorphisms such as stromal
derived factor 1 (SDF1-3'A), CCR2-64I, and CCR5-[DELTA] 32 associated with HIV-1 …

CCR-5 is a major cellular coreceptor for R5 strains of HIV-1. Individuals carrying a
homozygous 32-base-pair deletion in this gene are apparently healthy and are relatively …

Susceptibility of PHA/rIL-2-stimulated PBMC from 14 healthy blood donors for NSI HIV-1
infection was analyzed in relation to CCR5 expression and β-chemokine production. After 1 …

We studied the replication and cytopathicity in SCID-hu mice of R5 human
immunodeficiency virus type 1 (HIV-1) biological clones from early and late stages of …

Objective To investigate the relationship between CC chemokine receptor 5 (CCR5)
genotype, viral load and co-receptor usage of maternal HIV-1 isolates in perinatal HIV-1 …