BACKGROUND/AIM Proinflammatory cytokines are key factors in the pathogenesis of
Crohn's disease (CD). Activation of nuclear factor kappa B (NFκB), which is involved in their …

The therapeutic potential of cannabidiol (CBD), the major nonpsychoactive component of
cannabis, was explored in murine collagen-induced arthritis (CIA). CIA was elicited by …

Abstract mdash;: Sepsis remains a serious clinical problem despite intense efforts to
improve survival. Experimental animal models of sepsis have responded dramatically to …

Defence against viral infections in poultry consists of innate and adaptive mechanisms. The
innate defence is mainly formed by natural killer cells, granulocytes, and macrophages and …

By stimulating human lymphocytes with an autologous renal carcinoma, we obtained CTL
recognizing an antigen derived from a novel, ubiquitous protein. The CTL failed to lyse …

The immunomodulating properties of comb-like branched (1→ 3)-β-d-glucans scleroglucan,
schizophyllan and lentinan depend on branching pattern, molecular weight and higher …

IFN‐γ has been implicated in the pathogenesis of experimental cerebral malaria (ECM). We
have used mice lacking the α chain of the IFN‐γ receptor (KO mice) to define its role in the …

Lipopolysaccharide andd-galactosamine induced lethality and apoptotic liver injury is
dependent on endogenously produced tumor necrosis factor (TNF)-α. The present study …

An immunologic pathogenesis for amyotrophic lateral sclerosis (ALS) has been recently
proposed. We tested the whole tumour necrosis factor (TNF) system in the serum of 51 ALS …

The role of the CC chemokines, macrophage inflammatory protein-1β (MIP-1β), monocyte
chemotactic peptide-1 (MCP-1), and RANTES, in acute lung inflammatory injury induced by …