In patients with COPD, an acute worsening of respiratory symptoms is often described as an
exacerbation. Exacerbations are associated with a significant increase in mortality …

Respiratory tract infections may acutely increase risk from coronary heart disease (CHD),
though the mechanisms have not been defined. Patients with chronic obstructive pulmonary …

Although exacerbations of chronic obstructive pulmonary disease (COPD) are associated
with symptomatic and physiological deterioration, little is known of the time course and …

Objectives: To determine the effect of long term inhaled corticosteroids on lung function,
exacerbations, and health status in patients with moderate to severe chronic obstructive …

BACKGROUND Although it is presumed that exacerbations of chronic obstructive pulmonary
disease (COPD) are associated with increased airway inflammation, there is little …

Abstract Background and Objective: The aim of this study was to develop and validate two
models to estimate the probabilities of frequent exacerbations (more than 1 per year) and …

Infectious agents are a major cause of acute exacerbations of chronic bronchitis (AECB) and
COPD. Several respiratory viruses are associated with 30% of exacerbations, with or without …

Common colds are associated with exacerbations of chronic obstructive pulmonary disease
(COPD). However, the role of the common cold virus (human rhinovirus) in the production of …

BACKGROUND: The St. George's Respiratory Questionnaire (SGRQ) is a 50-item health
status survey specific for chronic obstructive pulmonary disease (COPD) and other …

There is little information available concerning the extent to which chronic obstructive
pulmonarv disease (COPD) patients are satisfactorily managed, especially, regards factors …