Imprinted genes represent a curious defiance of normal Mendelian genetics. Mammals
inherit two complete sets of chromosomes, one from the mother and one from the father, and …

Differences in DNA methylation distinguish the maternal and paternal alleles of many
imprinted genes. Allele-specific methylation that is inherited from the gametes and …

The gene encoding the insulin-like growth-factor type-2 receptor (Igf2r) is maternally
expressed and imprinted 1. A CpG island in Igf2r intron 2 that carries a maternal-specific …

Imprinted gene identification in animals has been limited to eutherian mammals, suggesting
a significant role for intrauterine fetal development in the evolution of imprinting. We report …

MBD1 belongs to a family of mammalian proteins that share a methyl-CpG binding domain.
Previous work has shown that MBD1 binds to methylated sites in vivo and in vitro and can …

Background Germline‐specific differential DNA methylation that persists through fertilization
and embryonic development is thought to be the 'imprint'distinguishing the parental alleles …

Igf2 and H19 are closely linked, reciprocally imprinted genes on mouse distal chromosome
7. The paternally expressed Igf2 encodes a potent fetal growth factor and the maternally …

Genomic imprinting is a special form of epigenetic system that determines the parent-of-
origin-specific, or monoallelic, expression of a small number of genes, termed" imprinted" …

The ability of maternal chromatin to support full-term development is attained during oocyte
growth. The aim of this study was to identify when during the growth phase the maternal …

Abstract Trichloroethylene (TCE), dichloroacetic acid (DCA), and trichloroacetic acid (TCA)
are environmental contaminants that are carcinogenic in mouse liver. 5-Methylcytosine (5 …