The structure of human β-defensin-2 shows evidence of higher order oligomerization
DM Hoover, KR Rajashankar, R Blumenthal… - Journal of Biological …, 2000 - ASBMB
Defensins are small cationic peptides that are crucial components of innate immunity,
serving as both antimicrobial agents and chemoattractant molecules. The specific …
serving as both antimicrobial agents and chemoattractant molecules. The specific …
Combinatorial libraries: a tool to design antimicrobial and antifungal peptide analogues having lytic specificities for structure–activity relationship studies
SE Blondelle, K Lohner - Peptide Science, 2000 - Wiley Online Library
In the race for supremacy, microbes are sprinting ahead. This warning by the World Health
Organization clearly demonstrates that the spread of antibiotic‐resistant bacteria leads to a …
Organization clearly demonstrates that the spread of antibiotic‐resistant bacteria leads to a …
Interaction of polyphemusin I and structural analogs with bacterial membranes, lipopolysaccharide, and lipid monolayers
L Zhang, MG Scott, H Yan, LD Mayer… - Biochemistry, 2000 - ACS Publications
Three structural variants (PV5, PV7, and PV8) of the horseshoe crab cationic antimicrobial
peptide polyphemusin I were designed with improved amphipathic profiles. Circular …
peptide polyphemusin I were designed with improved amphipathic profiles. Circular …
Conformational study of a custom antibacterial peptide cecropin B1: implications of the lytic activity
S Srisailam, AI Arunkumar, W Wang, C Yu… - Biochimica et Biophysica …, 2000 - Elsevier
Cecropin B1 (CB1) with two amphipathic α-helical segments is a derivative of the natural
antibacterial peptide, cecropin B. The assays of cell lysis show that, compared with cecropin …
antibacterial peptide, cecropin B. The assays of cell lysis show that, compared with cecropin …
Three-dimensional structure of RK-1: a novel α-defensin peptide
AM McManus, NF Dawson, JD Wade… - Biochemistry, 2000 - ACS Publications
NMR spectroscopy and simulated annealing calculations have been used to determine the
three-dimensional structure of RK-1, an antimicrobial peptide from rabbit kidney recently …
three-dimensional structure of RK-1, an antimicrobial peptide from rabbit kidney recently …
[HTML][HTML] Effects of the antibiotic peptide microcin J25 on liposomes: role of acyl chain length and negatively charged phospholipid
MR Rintoul, BF de Arcuri, RD Morero - Biochimica et Biophysica Acta (BBA) …, 2000 - Elsevier
This paper reports the effects of microcin J25 (MccJ25) on the microviscosity and
permeability of phospholipid vesicles of different compositions. The results obtained indicate …
permeability of phospholipid vesicles of different compositions. The results obtained indicate …
Human phospholipid binding proteins
P Lal, JL Hillman, NC Corley, P Shah - US Patent 6,063,767, 2000 - Google Patents
The invention provides two human phospholipid binding proteins (PLBP) and
polynucleotides which identify and encode PLBP. The invention also provides expression …
polynucleotides which identify and encode PLBP. The invention also provides expression …
Bacterial Evasion of Host‐Derived Antimicrobial Peptides on Mucosal Surfaces
KA Brogden - Virulence Mechanisms of Bacterial Pathogens, 2000 - Wiley Online Library
The small antimicrobial peptides found in phagocytic cells, epithelial cells, and on mucosal
surfaces and their mechanisms of antimicrobial killing have been reviewed recently. The …
surfaces and their mechanisms of antimicrobial killing have been reviewed recently. The …