Integrating basic and clinical research on the biophysical and physiological functions of
pulmonary surfactants, this practical reference presents thorough, cutting-edge coverage on …

Abstract Surfactant protein B (SP-B)−/− mice die of lethal respiratory distress syndrome
shortly after birth. Alveolar type II epithelial cells in SP-B–deficient mice are characterized by …

Objective. Surfactant protein B deficiency is a lethal cause of respiratory distress in infancy
that results most commonly from a homozygous frameshift mutation (121ins2). Using …

Infants with inherited deficiency of pulmonary surfactant protein (SP) B develop respiratory
failure at birth and die without lung transplantation. We examined aspects of surfactant …

IN THE 1920s the importance of surface tension in pulmonary physiology was first realized.
1 However, it was not until the 1950s that surfactant, a material obtained from alveolar …

Hereditary surfactant protein B (SP-B) deficiency is an uncommon autosomal recessive lung
disorder that causes hypoxemic respiratory failure in mature, morphologically normal infants …

Bij een voldragen pasgeborene ontstond enkele uren na de geboorte respiratoire
insufficiëntie. Door respiratoire ondersteuning met hoge beademingsvoorwaarden was de …

As in adults, the spectrum of diffuse lung disease (DLD) in children includes a large, diverse
group of rare pulmonary disorders that involve the pulmonary parenchyma and interfere with …