Both environmental tobacco smoke and indoor allergens can exacerbate already
established childhood albeit primarily through quite disparate mechanisms. In infancy and …

The spectrum of clinical asthma is broad, ranging from occasional mild wheezing or
coughing on exertion to severe, persistent disease that occasionally can be fatal. Asthma, by …

Immunoglobulin E (IgE) has a major role in the pathogenesis of allergic disorders and
asthma. Previous data from 92 families, each identified through a proband with asthma …

Asthma is a respiratory disorder characterized by airway hyperreactivity (AHR) and
inflammation and is associated with high serum IgE and overproduction of IL-4, IL-5, and IL …

Background Asthma morbidity and mortality are higher in the United States for African-
American (AA) children when compared to European-American (EA) children. Study …

Susceptibility to asthma and other atopic diseases is known to be associated with elevated
total IgE levels. Several investigators have linked the interleukin‐4 (IL‐4) gene and nearby …

Exposure to the well known environmental toxicant lead is typically assessed by blood
and/or bone levels and has been implicated in the onset of a variety of diseases affecting …

Hospital admissions and readmissions for asthma in early childhood remain causes for
concern. The purpose of this study was to identify predisposing risk factors related to asthma …

OBJECTIVE: A 23-year followup study of 1,601 college students who were initially evaluated
for evidence of asthma and allergic rhinitis by direct interviews, physical examination …

Asthma is characterized by bronchial hyperresponsiveness to a variety of
bronchospasmogenic stimuli. To study the pathophysiologic mechanisms underlying the …