Dietary nucleotides, like glutamine, have attracted attention as a key ingredient missing from
nutritional formulae for many years. They are the building blocks of tissue RNA and DNA …

Leishmania parasites are transmitted to their vertebrate hosts by infected phlebotomine
sand fly bites. Sand fly saliva is known to enhance Leishmania infection, while immunity to …

Adenosine, acting at its receptors, particularly A 2A receptors, is a potent endogenous anti-
inflammatory agent that modulates the functions and differentiation of inflammatory and …

Dendritic cells (DCs) are specialized antigen‐presenting cells characterized by their ability
to migrate into target sites, process antigens, and activate naive T cells. In this study, we …

The sympathetic nervous system plays a central role in establishing communication
between the central nervous system and the immune system during inflammation …

Inosine is a naturally occurring purine formed from the breakdown of adenosine. Here we
have evaluated the effects of inosine in a murine model of polymicrobial sepsis induced by …

In murine bone marrow macrophages, lipopolysaccharide (LPS) induces apoptosis through
the autocrine production of tumor necrosis factor-α (TNF-α), as demonstrated by the fact that …

Inosine is an endogenous purine, which has been recently shown to exert
immunomodulatory, anti-inflammatory and anti-shock effects in rodent experimental …

It is increasingly apparent that there is a bidirectional interaction between the maternal
immune system and the reproductive system during pregnancy. Pregnancy is associated …

Background: We hypothesized that systemic ATL-146e, an adenosine A2A agonist, would
decrease spinal cord reperfusion inflammatory stress and inhibit apoptosis and that these …