The replication cycle of the human cytomegalovirus (HCMV) is characterized by the
expression of immediate early (IE), early (E), and late (L) gene regions. Current antiviral …

Reactivation of cytomegalovirus (CMV) from latency is a frequent complication of organ
transplantation, and the molecular mechanism by which this occurs is unknown. Previous …

Infectious clone methodology is a valuable tool of modern experimental virology. However,
its use is often constrained by the instability of infectious clone constructs during propagation …

PURPOSE: Diabetic cystopathy resulting from sensory neuropathy may potentially be
treated by direct gene therapy. It has been suggested that nerve growth factor (NGF) has an …

The 'infectious DNA'approach, which is based on in vivo transcription of (+) RNA virus
genome cDNA cassettes from eukaryotic promoters in transfected cells, became a popular …

The immediate‐early (IE) promoter of human cytomegalovirus (HCMV) constitutes a primary
genetic switch, which determines the progression of viral infection. Earlier reports by others …

Cytomegalovirus infection is a major cause of morbidity in immunocompromised patients.
The major immediate early promoter/enhancer (MIEP) of the human cytomegalovirus …

Swinepox virus belongs to the family Poxviridae. Viruses belonging to this group are large,
double-stranded DNA viruses that characteristically develop in the cytoplasm of the host cell …

Amphotropic murine leukemia virus (MLV) can replicate in human cells and is a potential
contaminant in vector preparations for human gene transfer studies. We have recently …

Swinepox virus belongs to the family Poxviridae. Viruses belonging to this group are large,
double-stranded DNA viruses that characteristically develop in the cytoplasm of the host cell …