In this brief summary, we argue that many widely held beliefs about HLA-G are
questionable. Recent research has led to a re-evaluation of many of the characteristics that …

HLA-G is a nonclassical MHC class I molecule that plays a major role in maternal-fetal
tolerance. Four membrane-bound (HLA-G1 to-G4) and two soluble (HLA-G5, and-G6) …

Studies in humans suggest that reproductive failure may be influenced by immunological
factors or by genes encoding immunological factors and regulatory mechanisms controlling …

Soluble HLA‐G (sHLA‐G) molecules are found in the peripheral blood of healthy females
and males, in cord blood and in amniotic fluids and discussed to be a mediator in maternal …

Immune evasion in lung cancer results from both structural and functional alterations of
human leukocyte antigen (HLA) class I molecules and the local release of …

HLA-G is a nonclassical class I antigen mainly expressed at the maternofetal interface
during pregnancy where it is thought to downmodulate maternal immune response against …

Exquisitely regulated cytokine balance during early pregnancy is thought to be necessary for
promoting survival of the fetal allograft. Our previous studies have demonstrated that …

Recent data have suggested that in psoriasis, the T-infiltrating cells could be submitted to
regulatory pathways, possibly through natural killer receptors. HLA-G binds to different …

It is now acknowledged that the pattern of HLA-G expression is not restricted to extravillous
cytotrophoblast cells, as several studies described HLA-G in HLA class I+ cells, such as …

The human MHC class Ib antigen HLA-G is thought to regulate maternal immune responses
during pregnancy. Here we show that expression of HLA-G in transgenic mice diminished …