Respiratory muscle strength and ventilatory failure in amyotrophic lateral sclerosis

RA Lyall, N Donaldson, MI Polkey, PN Leigh… - Brain, 2001 - academic.oup.com
Although ventilatory failure is the most common cause of death in amyotrophic lateral
sclerosis (ALS) and measurement of respiratory muscle strength (RMS) has been shown to …

The effect of non-invasive positive pressure ventilation (NIPPV) on cognitive function in amyotrophic lateral sclerosis (ALS): a prospective study

IC Newsom-Davis, RA Lyall, PN Leigh… - Journal of Neurology …, 2001 - jnnp.bmj.com
OBJECTIVES Neuropsychological investigations have shown a degree of cognitive
dysfunction in a proportion of non-demented patients with ALS. Respiratory muscle …

Respiratory function vs sleep-disordered breathing as predictors of QOL in ALS

SC Bourke, PJ Shaw, GJ Gibson - Neurology, 2001 - AAN Enterprises
Background: Most patients with ALS have evidence of respiratory muscle weakness at
diagnosis, and death is usually due to respiratory failure. Sleep disruption, possibly due to …

Age-dependent poliomyelitis in mice is associated with respiratory failure and viral replication in the central nervous system and lung

EH Schlenker, QA Jones, RRR Rowland… - Journal of …, 2001 - Taylor & Francis
Age-dependent poliomyelitis (ADPM) is a virally induced neuroparalytic disease of mice and
a model for amyotrophic lateral sclerosis (ALS). ADPM is triggered in genetically susceptible …