This article describes methodological decisions that have to be made when studying
multiple pathology and presents appropriate analytical techniques. The main question of this …

Older males are known to carry, more likely than younger people, one or more chronic
diseases with an expected impact on mortality. This study was aimed at identifying the …

Objective Psychiatric and somatic disorders frequently co-occur in the same individuals. We
examined whether this happens because these types of morbidity share risk factors or …

Objective: The aim of this study was to get a profile of patients who are vulnerable to get
multiple chronic, recurrent or high-impact diseases in a limited time period. We studied the …

Background The segment of patients with advanced coronary artery disease, or disease that
is not amenable to conventional revascularization therapies, continues to grow. Because the …

This supplement contains a series of papers supporting the justification, design, and
implementation of a longitudinal cohort study of an aging HIV-positive and HIV-negative …

Background. This study reports findings for laparoscopic nephrectomy in comparison with
open nephrectomy in geriatric patients. Methods. Since 1993, a total of 249 patients have …

Abstract In 1995 the Medical Faculty of the University Medical Center of Nijmegen revised its
curriculum to be more problem-oriented and student-centered. Each of the first four years …

Background. For women with chronic conditions, care often concentrates on the underlying
disorder to the exclusion of cancer screening recommendations. This occurs in the face of …