Although the general idea of 'burden'of a disease to a community seems fairly
straightforward, there are multiple dimensions in which it may be expressed, either in terms …

Chronic infection with the hepatitis B virus (HBV) is estimated to affect 400 million persons
and to be the single most common cause of cirrhosis and hepatocellular carcinoma (HCC) …

Hepatocellular carcinoma (HCC) is a neoplasm the incidence of which is increasing
worldwide, but striking geographical differences are observed for both risk factors and …

The discipline of infectious diseases will assume added prominence in the 21st century in
both developed and developing nations. To an unprecedented extent, issues related to …

Background: Studies in animal models have shown that systemic immunization with a
papillomavirus virus-like particle (VLP) vaccine composed of L1, a major structural viral …

Abstract Background: The American Cancer Society, the National Cancer Institute (NCI), the
North American Association of Central Cancer Registries, and the Centers for Disease …

Chronic hepatitis B virus (HBV) infection is a major global cause of hepatocellular carcinoma
(HCC). Individuals who are chronic carriers have a greater than 100‐fold increased relative …

Residents of Qidong, People's Republic of China, are at high risk for development of
hepatocellular carcinoma, in part from consumption of foods contaminated with aflatoxins …

In the recent decades, the incidence of hepatocellular carcinoma (HCC) has been found to
be increasing in males in some countries. In China, HCC ranked second of cancer mortality …

Primary liver cancer (PLC) is common in many areas of the developing world, but
uncommon in most of the developed world. Some evidence suggests, however, that the …