Origin, differentiation and regulation of fetal and adult Leydig cells

R Habert, H Lejeune, JM Saez - Molecular and cellular endocrinology, 2001 - Elsevier
Mammalian sex determination involves complex interacting networks of cellular and
hormonal signals leading to the development of male or female phenotype. Three main …

Lutropin Receptor Function: Insights from Natural, Engineered, and Computer‐Simulated Mutations

F Fanelli, APN Themmen, D Puett - IUBMB life, 2001 - Wiley Online Library
The lutropin receptor is a member of the superfamily of G protein‐coupled receptors and, in
humans, binds two closely related ligands, members of the heterodimer glycoprotein …

A novel homozygous mutation in the second transmembrane domain of the gonadotrophin releasing hormone receptor gene

D Söderlund, P Canto, E De La Chesnaye… - Clinical …, 2001 - Wiley Online Library
BACKGROUND and OBJECTIVE Mutations in the GnRH receptor (GnRH‐R) gene cause
hypogonadotrophic hypogonadism. Here, we present the molecular studies of the GnRH‐R …

Micropenis and the AR gene: mutation and CAG repeat-length analysis

T Ishii, S Sato, K Kosaki, G Sasaki… - The Journal of …, 2001 - academic.oup.com
Various mutations of the AR gene and expanded CAG repeats at exon 1 of that gene have
been reported in patients with hypospadias or genital ambiguity. However, the role of the AR …

[HTML][HTML] Receptores acoplados à proteína G: implicações para a fisiologia e doenças endócrinas

OM Hauache - Arquivos Brasileiros de Endocrinologia & Metabologia, 2001 - SciELO Brasil
A maioria dos hormônios polipeptídicos e mesmo o cálcio extracelular atuam em suas
células-alvo através de receptores acoplados à proteína G (GPCRs). Nos últimos anos, tem …

单个基因突变导致女性生殖功能紊乱

李东至, 林其德 - 国外医学: 计划生育分册, 2001 - cqvip.com
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[HTML][HTML] O papel dos receptores das gonadotrofinas na reprodução feminina

MBF Kohek, AC Latronico - Arquivos Brasileiros de Endocrinologia & …, 2001 - SciELO Brasil
As ações fundamentais das gonadotrofinas hipofisárias na vida sexual reprodutiva de
ambos os sexos dependem da integridade estrutural e funcional dos seus respectivos …

Du constat pathologique à l'obtention de l'ovulation. Le cas des déficiences ovariennes

P Barbarino-Monnier - Gynécologie obstétrique & fertilité, 2001 - Elsevier
Résumé Un à 3% de la population est concerné par le diagnostic de ménopause précoce.
Par définition, cette défaillance ovarienne survient chez des patientes jeunes, qui ont …

Genetically controlled hormonal regulation of human sexual differentiation and reproductive system development

VB Chernykh, LF Kurilo - Russian Journal of Genetics, 2001 - Springer
Literature data on genetic control of hormonal regulation of sexual differentiation and
reproduction system development in humans are reviewed. The conditions caused by …

Gonadotropin hormones: disorders

JC Achermann, JL Jameson - e LS, 2001 - Wiley Online Library
Abnormalities in gonadotropin hormone release and function can arise from mutations in a
variety of genes expressed throughout the hypothalamic–pituitary (gonadotrope)–gonadal …