Genomic imprinting affects several dozen mammalian genes and results in the expression of
those genes from only one of the two parental chromosomes. This is brought about by …

KCNQ genes encode a growing family of six transmembrane domains, single pore-loop, K+
channel α-subunits that have a wide range of physiological correlates. KCNQ1 (KvLTQ1) is …

The heterotrimeric G protein Gs couples hormone receptors (as well as other receptors) to
the effector enzyme adenylyl cyclase and is therefore required for hormone-stimulated …

Abstract Changes in DNA methylation profiles are common features of development and in a
number of human diseases, such as cancer and imprinting disorders like Beckwith …

Dysregulation of imprinted genes on human chromosome 11p15 has been implicated in
Beckwith–Wiedemann syndrome (BWS), an overgrowth syndrome associated with …

The imprinted UBE3A gene exhibits maternal-only expression in specific cell types in the
brain, but exhibits biallelic expression in other cell types. UBE3A is located adjacent to a …

Beckwith–Wiedemann syndrome (BWS) is an overgrowth disorder involving developmental
abnormalities, tissue and organ hyperplasia and an increased risk of embryonal tumours …

Beckwith–Wiedemann syndrome (BWS) is an overgrowth malformation syndrome that maps
to human chromosome 11p15. 5, a region that harbours a number of imprinted genes. We …

Uniparental disomy represents a departure from the usual situation in which one member of
each pair of chromosomes (called homologous chromosomes) is normally inherited from …

The non-coding RNAs database (http://biobases. ibch. poznan. pl/ncRNA/) contains
currently available data on RNAs, which do not have long open reading frames and act as …