Summary Background Background Activated microglia have a key role in the brain's
immune response to neuronal degeneration. The transition of microglia from the normal …

Intrathecal infusions are used in a number of rodent studies to deliver substances to the
injured spinal cord. Whereas this method has been successful in certain paradigms, two …

A major challenge in the assessment of brain injury and its relationship to the ensuing
functional deficits is the accurate delineation of the areas of damage. Here, we test the …

Limb denervation leads to reorganization of the representational zones of the
somatosensory cortex. Using [11 C](R)-PK11195, a sensitive in vivo marker of glial cell …

Microglia, as intrinsic immunoeffector cells of the central nervous system (CNS), play a very
sensitive, crucial role in the response to almost any brain pathology where they are activated …

Magnetic resonance imaging methods allow observation of pathological changes in vivo.
Magnetic resonance-based studies have provided a number of important insights into the …

Based on the development of a transgenic animal model, an increasing number of
experimental strategies have revealed the potential to modify the selective degeneration of …

In an editorial commenting on a recent article on MRI enhancing lesions and T2 load as a
marker of the latter). A relatively straightforward hypothesis could be proposed to evaluation …