Alzheimer's disease (AD) is a progressive dementing neurologic illness, and the most
frequent cause of dementia in the elderly. Neuritic plaques are one of the main …

Peroxisome proliferator-activated receptor (PPAR) γ belongs to the nuclear receptor
superfamily of ligand-dependent transcription factors. Recent results have shown that the …

Microglia are activated in humans following infection with human immunodeficiency virus
(HIV), and brain inflammation is thought to be involved in neuronal injury and dysfunction …

Alzheimer's disease (AD) is an irreversible, progressive brain disorder that occurs gradually
and results in memory loss, behavior and personality changes, and a decline in cognitive …

The accumulation of fibrillar aggregates of beta Amyloid (Aβ) in Alzheimer's Disease (AD)
brain is associated with chronic brain inflammation. Although activated microglia (μglia) can …

Globoid cell leukodystrophy is one of the classical genetic leukodystrophies in humans. The
typical infantile disease in man (Krabbe disease) is caused by deficiency of lysosomal …

The cause of Alzheimer's disease is closely associated with the accumulation of β-amyloid
in the neocortex. The neurochemical factors responsible for precipitating this otherwise …

Estrogen replacement therapy in postmenopausal women is associated with decreased risk
for Alzheimer's Disease (AD) or delay in disease onset. The mechanism by which estrogen …