Effects of Macromolecular Crowding on the Intrinsically Disordered Proteins c-Fos and p27Kip1
SL Flaugh, KJ Lumb - Biomacromolecules, 2001 - ACS Publications
A number of biologically active proteins exhibit intrinsic structural disorder in vitro under
thermodynamically ideal conditions. In vivo, however, proteins exist in a crowded …
thermodynamically ideal conditions. In vivo, however, proteins exist in a crowded …
How transcriptional activators bind target proteins
S Hermann, KD Berndt, AP Wright - Journal of Biological Chemistry, 2001 - ASBMB
The product of the proto-oncogene c-myc influences many cellular processes through the
regulation of specific target genes. Through its transactivation domain (TAD), c-Myc protein …
regulation of specific target genes. Through its transactivation domain (TAD), c-Myc protein …
Transcriptional activity of the TFIIA four‐helix bundle in vivo
LA Stargell, RC Ogg, JN Adkins… - Proteins: Structure …, 2001 - Wiley Online Library
TFIIA contributes to transcription initiation by stabilizing the TBP–TATA interaction and by
mediating the response to transcriptional activators and inhibitors. TFIIA contains a six …
mediating the response to transcriptional activators and inhibitors. TFIIA contains a six …
[图书][B] Cyclin A-Cdk2 inhibition by p21, p27, and p57
JN Adkins - 2001 - search.proquest.com
Cyclin-dependent kinases (Cdks) are regulated through several mechanisms, including
negative regulation by the p21 family of inhibitors. It has been proposed that multiple p21 …
negative regulation by the p21 family of inhibitors. It has been proposed that multiple p21 …
[PDF][PDF] Unravelling vascular tumors: combining molecular and computational biology
DGP IJzendoorn - gene, 2001 - scholarlypublications …
Epithelioid hemangioma is a locally aggressive vascular neoplasm, found in bones and soft
tissue, whose cause is currently unknown, but may involve oncogene activation. FOS is one …
tissue, whose cause is currently unknown, but may involve oncogene activation. FOS is one …