Sarcopenia
JE Morley, RN Baumgartner, R Roubenoff… - Journal of Laboratory …, 2001 - Elsevier
Sarcopenia is a term utilized to define the loss of muscle mass and strength that occurs with
aging. Sarcopenia is believed to play a major role in the pathogenesis of frailty and …
aging. Sarcopenia is believed to play a major role in the pathogenesis of frailty and …
Ciliary neurotrophic factor activates leptin-like pathways and reduces body fat, without cachexia or rebound weight gain, even in leptin-resistant obesity
PD Lambert, KD Anderson… - Proceedings of the …, 2001 - National Acad Sciences
Ciliary Neurotrophic Factor (CNTF) was first characterized as a trophic factor for motor
neurons in the ciliary ganglion and spinal cord, leading to its evaluation in humans suffering …
neurons in the ciliary ganglion and spinal cord, leading to its evaluation in humans suffering …
Neuroprotective effect of a CNTF-expressing lentiviral vector in the quinolinic acid rat model of Huntington's disease
Neurodegenerative diseases represent promising targets for gene therapy approaches
provided effective transfer vectors. In the present study, we evaluated the effectiveness of …
provided effective transfer vectors. In the present study, we evaluated the effectiveness of …
CNTF genotype is associated with muscular strength and quality in humans across the adult age span
SM Roth, MA Schrager, RE Ferrell… - Journal of applied …, 2001 - journals.physiology.org
The relationship between ciliary neurotrophic factor (CNTF) genotype and muscle strength
was examined in 494 healthy men and women across the entire adult age span (20–90 yr) …
was examined in 494 healthy men and women across the entire adult age span (20–90 yr) …
Neuronal targeting of cardiotrophin-1 by coupling with tetanus toxin C fragment
T Bordet, L Castelnau-Ptakhine, F Fauchereau… - Molecular and Cellular …, 2001 - Elsevier
Cardiotrophin-1 (CT-1) is a potent neurotrophic factor for motoneurons but its clinical use in
motor neuron diseases is precluded by side effects on the heart and liver. We explored the …
motor neuron diseases is precluded by side effects on the heart and liver. We explored the …
Intracerebral infusion of a second-generation ciliary neurotrophic factor reduces neuronal loss in rat striatum following experimental intracerebral hemorrhage
MR Del Bigio, HJ Yan, M Xue - Journal of the neurological sciences, 2001 - Elsevier
Neuronal and glial cell death in the striatum of a rat model of collagenase-induced
intracerebral hemorrhage begins at 1 day and continues for at least 3 weeks. We …
intracerebral hemorrhage begins at 1 day and continues for at least 3 weeks. We …
Metabolic abnormalities in advanced pancreatic cancer and their modulation by an eicosapentaenoic acid-based preparation
MD Barber - 2001 - theses.gla.ac.uk
A combination of a nutritional supplement and eicosapentaenoic acid was given to patients
with advanced pancreatic cancer to assess its effect on the ongoing cachectic process. The …
with advanced pancreatic cancer to assess its effect on the ongoing cachectic process. The …