Mitochondrial involvement in brain function and dysfunction: relevance to aging, neurodegenerative disorders and longevity
V Calabrese, G Scapagnini, AM Giuffrida Stella… - Neurochemical …, 2001 - Springer
It is becoming increasingly evident that the mitochondrial genome may play a key role in
neurodegenerative diseases. Mitochondrial dysfunction is characteristic of several …
neurodegenerative diseases. Mitochondrial dysfunction is characteristic of several …
Neurotoxic Aβ peptides increase oxidative stress in vivo through NMDA‐receptor and nitric‐oxide‐synthase mechanisms, and inhibit complex IV activity and induce a …
JK Parks, TS Smith, PA Trimmer… - Journal of …, 2001 - Wiley Online Library
Beta amyloid (Aβ) peptides accumulate in Alzheimer's disease and are neurotoxic possibly
through the production of oxygen free radicals. Using brain microdialysis we characterized …
through the production of oxygen free radicals. Using brain microdialysis we characterized …
Amyloid β-peptide disrupts mitochondrial membrane lipid and protein structure: protective role of tauroursodeoxycholate
CMP Rodrigues, S Solá, MA Brito, CD Brondino… - Biochemical and …, 2001 - Elsevier
Mitochondria have been implicated in the cytotoxicity of amyloid β-peptide (Aβ), which
accumulates as senile plaques in the brain of Alzheimer's disease patients …
accumulates as senile plaques in the brain of Alzheimer's disease patients …
Effects of aging and β-amyloid on the properties of brain synaptic and mitochondrial membranes
The effects of aging and of different amyloid β-peptides (Aβ) on the properties of purified
synaptosomal plasma and mitochondrial membranes were studied using different …
synaptosomal plasma and mitochondrial membranes were studied using different …
The action of acetyl‐l‐carnitine on the neurotoxicity evoked by amyloid fragments and peroxide on primary rat cortical neurones
MA Virmani, V Caso, A Spadoni, S Rossi… - Annals of the New …, 2001 - Wiley Online Library
The amyloid β‐peptides have been implicated in the excitotoxic mechanism of neuronal
injury in the pathogenesis of Alzheimer's disease. In this paper we examine the effect of …
injury in the pathogenesis of Alzheimer's disease. In this paper we examine the effect of …
[图书][B] Molekularna osnova genetičkih rearanžmana izazvanih IS5 elementima u polA1 mutatorskom soju Escherichia coli K12
T Kostić - 2001 - search.proquest.com
U našem prethodnom radu na polA1 mutantima pokazali smo da polA1 kreira mutacije
isključivo tipa minus fs i delecija. U mutacionom spektru histidinskih auksotrofa bila je …
isključivo tipa minus fs i delecija. U mutacionom spektru histidinskih auksotrofa bila je …
[图书][B] Role of mitochondria in the neuroprotective effects of estrogen
J Wang - 2001 - search.proquest.com
Estrogen replacement therapy in postmenopausal women is associated with decreased risk
for Alzheimer's Disease (AD) or delay in disease onset. The mechanism by which estrogen …
for Alzheimer's Disease (AD) or delay in disease onset. The mechanism by which estrogen …