Type II secretion and pathogenesis

M Sandkvist - Infection and immunity, 2001 - Am Soc Microbiol
Extracellular secretion of proteins is regarded as a major virulence mechanism in bacterial
infection. Proteins destined for the extracellular environment of gram-negative bacteria have …

Protein secretion and the pathogenesis of bacterial infections

VT Lee, O Schneewind - Genes & development, 2001 - genesdev.cshlp.org
The skin, the oral cavity, and the gastrointestinal tract of humans are colonized with bacteria.
Microbial entry into the blood or blood-circulated tissues is hindered by anatomical barriers …

Phylogeny of genes for secretion NTPases: Identification of the widespread tadA subfamily and development of a diagnostic key for gene classification

PJ Planet, SC Kachlany, R DeSalle… - Proceedings of the …, 2001 - National Acad Sciences
Macromolecular transport systems in bacteria currently are classified by function and
sequence comparisons into five basic types. In this classification system, type II and type IV …

High Extracellular Levels of Mycobacterium tuberculosis Glutamine Synthetase and Superoxide Dismutase in Actively Growing Cultures Are Due to High Expression …

MV Tullius, G Harth, MA Horwitz - Infection and immunity, 2001 - Am Soc Microbiol
Glutamine synthetase (GS) and superoxide dismutase (SOD), large multimeric enzymes that
are thought to play important roles in the pathogenicity of Mycobacterium tuberculosis, are …

Conjugal type IV macromolecular transfer systems of Gram-negative bacteria: organismal distribution, structural constraints and evolutionary conclusions

TB Cao, MH Saier Jr - Microbiology, 2001 - microbiologyresearch.org
Background Over a dozen distinct families of transport systems that catalyse translocation of
proteins across cytoplasmic membranes have been recognized, characterized and …

The AprX protein of Pseudomonas aeruginosa: a new substrate for the Apr type I secretion system

F Duong, E Bonnet, V Géli, A Lazdunski, M Murgier… - Gene, 2001 - Elsevier
Protein secretion in Pseudomonas aeruginosa involves different mechanisms. The type II
and type III secretory pathways control the extracellular release of a wide range of …

The catalytic activities of the bifunctional Azotobacter vinelandii mannuronan C-5-epimerase and alginate lyase AlgE7 probably originate from the same active site in …

BIG Svanem, WI Strand, H Ertesvåg… - Journal of Biological …, 2001 - ASBMB
The Azotobacter vinelandii genome encodes a family of seven secreted Ca 2+-dependent
epimerases (AlgE1–7) catalyzing the polymer level epimerization of β-d-mannuronic acid …

ABC transporters and the export of capsular polysaccharides from gram-negative bacteria

RP Silver, K Prior, C Nsahlai, LF Wright - Research in microbiology, 2001 - Elsevier
In this review, we discuss the kps cluster of Escherichia coli as the paradigm for the ABC
capsular polysaccharide exporter (CPSE) family. Components of the cluster form a …

The carboxy‐terminus of VirE2 from Agrobacterium tumefaciens is required for its transport to host cells by the virB‐encoded type IV transport system

M Simone, CA McCullen, LE Stahl… - Molecular …, 2001 - Wiley Online Library
Agrobacterium tumefaciens transfers DNA from the resident 'tumour‐inducing'(Ti) plasmid
into plant cells, where it can be stably integrated into the plant genome, ultimately resulting …

Nonspecific Adherence and Fibril Biogenesis by Actinobacillus actinomycetemcomitans: TadA Protein Is an ATPase

MK Bhattacharjee, SC Kachlany, DH Fine… - Journal of …, 2001 - Am Soc Microbiol
Cells of Actinobacillus actinomycetemcomitans, a gram-negative pathogen responsible for
an aggressive form of juvenile periodontitis, form tenaciously adherent biofilms on solid …