Gene therapy for hypertension: the preclinical data

MI Phillips - Hypertension, 2001 - Am Heart Assoc
Despite several drugs for the treatment of hypertension, there are many patients with poorly
controlled high blood pressure. This is partly because all of the available drugs are short …

Mouse models of blood pressure regulation and hypertension

F Sugiyama, K Yagami, B Paigen - Current hypertension reports, 2001 - Springer
Human essential hypertension is recognized as a multifactorial disease involving many
genes, but the causative genes have not yet been identified. For many years hypertension …

Determination of catecholamines and their 3‐O‐methyl metabolites in mouse plasma

M Tsunoda, K Takezawa, T Yanagisawa… - Biomedical …, 2001 - Wiley Online Library
The determination of catecholamines and their 3‐O‐methyl metabolites in a single mouse
plasma is necessary to understand the role of the sympathetic nervous activity, while the …

Lack of correlation between Mbo I restriction fragment length polymorphism of renin gene and essential hypertension in Japanese

Y FU, T KATSUYA, T ASAI, M FUKUDA… - Hypertension …, 2001 - jstage.jst.go.jp
抄録 Predisposition to essential hypertension is associated with gene polymorphisms of the
renin angiotensin system (RAS). Gene polymorphisms of the angiotensinogen and …

Method to determine predisposition to hypertension

A Rohrwasser, JM Lalouel - US Patent 6,177,252, 2001 - Google Patents
Abstract The T/C (67) AGT gene variant and the association of the molecular variant C (67)
with predisposition of an individual to hypertension are disclosed. The determination of this …

[图书][B] Viral vector mediated gene therapy in multiple models of hypertension

AS Pachori - 2001 - search.proquest.com
Hypertension is a very complex and debilitating disease. Clinical and experimental studies
have implicated a role of the hyperactive circulatory and tissue renin-angiotensin system …