Use of statins in CNS disorders

B Cucchiara, SE Kasner - Journal of the neurological sciences, 2001 - Elsevier
It is well established that 3-hydroxy-3-methyglutaryl coenzyme A (HMG-CoA) reductase
inhibitors (“statins”) reduce cholesterol levels and prevent coronary heart disease (CHD) …

T-cell immunity in acute coronary syndromes

CM Weyand, JJ Goronzy, G Liuzzo, SL Kopecky… - Mayo Clinic …, 2001 - Elsevier
Acute coronary syndromes (ACS) are complications of atherosclerotic vascular disease that
are triggered by the sudden rupture of an atheroma. Atherosclerotic plaque stability is …

Carotid stenosis: factors affecting symptomatology

CD Liapis, JD Kakisis, AG Kostakis - Stroke, 2001 - Am Heart Assoc
Background and Purpose—The ability to predict future strokes in asymptomatic patients with
carotid stenosis is currently limited. The management of symptomatic patients with< 50 …

Expression of tissue factor in high-grade carotid artery stenosis: association with plaque destabilization

S Jander, M Sitzer, A Wendt, M Schroeter… - Stroke, 2001 - Am Heart Assoc
Background and Purpose—The procoagulant protein tissue factor (TF) has been implicated
in thromboembolic complications associated with advanced atherosclerosis. In this study …

The discovery of the pathophysiological aspects of atherosclerosis—a review

H Hanke, C Lenz, G Finking - Acta Chirurgica Belgica, 2001 - Taylor & Francis
Considering the morphological findings in egyptian mummies at the beginning of the 20th
century, atherosclerotic lesions were also apparent in pharaoh mummies more than 3500 …

Cerebrovascular events in patients with significant stenosis of the carotid artery are associated with hyperhomocysteinemia and platelet antigen-1 (Leu33Pro) …

JY Streifler, N Rosenberg, A Chetrit, R Eskaraev… - Stroke, 2001 - Am Heart Assoc
Background and Purpose—Although risk factors for carotid artery stenosis caused by
atherosclerosis are known, it is unclear what triggers “activation” of the atherosclerotic …

Increased CD8+ T Cells Associated With Chlamydia pneumoniae in Symptomatic Carotid Plaque

ZG Nadareishvili, DE Koziol, B Szekely, C Ruetzler… - Stroke, 2001 - Am Heart Assoc
Background and Purpose—The presence of Chlamydia pneumoniae has been reported in
carotid atheroma, but its causative effect in the activation of an atherosclerotic plaque to a …

Immunophenotypic characterisation of carotid plaque: increased amount of inflammatory cells as an independent predictor for ischaemic symptoms

H Schumacher, E Kaiser, PA Schnabel, J Sykora… - European Journal of …, 2001 - Elsevier
Objectives to investigate the inflammatory response within intact carotid plaques from carotid
eversion endarterectomy (CEE) to determine the relationship between immunohistological …

[HTML][HTML] Determinants of carotid microembolization

J Golledge, R Gibbs, C Irving, G Clayton, D Bond… - Journal of vascular …, 2001 - Elsevier
Purpose: Earlier studies have highlighted risk factors for perioperative stroke after carotid
endarterectomy, such as female sex, preoperative symptoms, and cerebral infarction. In this …

Differences in the detection of cyclo‐oxygenase 1 and 2 proteins in symptomatic and asymptomatic carotid plaques

SM Wijeyaratne, CR Abbott… - British journal of …, 2001 - Wiley Online Library
Background: The expression of cyclo‐oxygenase (COX) 1 and 2 has been demonstrated in
atherosclerotic arteries. In the present study this was correlated with symptoms arising from …